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71984 WideScreen® Human Cancer Panel 1

71984
  
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      Overview

      Replacement Information

      This product has been replaced by WideScreen® BeadPlex™ Human Cancer Panel 1 (Cat. No. BPHCP001-6)



      The WideScreen® Human Cancer Panel 1 (Tumor Markers) is a pre-mixed multiplex bead kit of quantitative antibody-based assays for simultaneous detection of six tumor-associated human proteins found in biological fluids: AFP (a-fetoprotein), CA 125, CA15-3, CA 19-9, CEA (carcinoembryonic antigen), and prolactin. The kit includes all the reagents, controls, and buffers needed to analyze the above proteins in serum, plasma, and tissue culture supernatants using the Luminex® xMAP® System.

      The WideScreen® Human Cancer Panel 1 uses the same reagents and technologies developed by Rules Based Medicine for the use in their industry-leading biomarker testing service along with the expertise of Novagen in commercializing and supporting high value products. Accordingly, the kits are supplied with the highest quality and relevant validation data, ensuring that each assay kit meets the stringent quality and performance required in today’s demanding research environment.



      Description

      Performance Characteristics

      Species

      Human, other species not tested

      Sample Size

      6 µl

      Sample Types

       

      Serum, plasma, tissue culture supernatants

       

      Linearity
      % recovery across dilutions

      Dilution


      1:10
      1:20
      1:40
      Range
      91%-111%
      92%-103%
      93%-111%


      Intra-assay CV

      3%-15%
      Inter-assay CV
      7%-24%

      Cross-reactivity

       

      Negligible

       

      Matrix Interference
      Analyte recovery in the
      presence of
      :

      Hemoglobin (5mg/ml) 72% to 100% 
      Bilirubin (0.2 mg/ml) 81% to 92%
      Triglycerides (5mg/ml) 101% to 126%

      Analyte
      Standard Range
      Assay LDD
      Average Recovery
      from Serum
      Average Recovery
      from EDTA Plasma
      Normal Range*
      AFP
      0.15-333 ng/ml
      0.15 ng/ml
      92%
      101%
      <20 ng/ml
      CA 125
      0.55-1200 U/ml
      0.30 U/ml
      144%
      131%
      <35 U/ml
      CA 15-3
      0.18-392 U/ml
      0.18 U/ml
      96%
      108%
      <25 U/ml
      CA 19-9
      0.15-320 U/ml
      0.15 U/ml
      87%
      98%
      <37 U/ml
      CEA
      0.017-37 ng/ml
      0.017 ng/ml
      76%
      84%
      <5 ng/ml
      Prolactin
      0.017-38 ng/ml
      0.017 ng/ml
      72%
      74%
      <29 ng/ml**

      *Normal range data from American Cancer Society website, www.cancer.org and other sources.
      **Pregnant women: 10-209 ng/ml

      Catalogue Number71984 Brand Family Novagen®
      References
      Product Information
      Human Cancer Panel 1 Standards Mix
      Human Cancer Panel 1 Control 1
      Human Cancer Panel 1 Control 2
      1X Assay Buffer Type 2
      Blocking Buffer Type 1
      1X Sample Dilution Buffer Type 1
      Standard Curve Diluent Type 1
      15X Streptavidin-Phycoerythrin
      Human Cancer Panel 1 Capture Beads
      Human Cancer Panel 1 Detection Antibodies
      96-well Filter Plate and Sealer
      Applications
      Biological Information
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      S PhraseS: 26-36/37/39-45

      In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
      Wear suitable protective clothing, gloves and eye/face protection.
      In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Blue Ice Only
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Do not freeze Ok to freeze
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      71984 0