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428035 Anti-HOCl-Oxidized Low Density Lipoprotein Rabbit pAb

428035
Purchase on Sigma-Aldrich

Panoramica

Replacement Information

Tabella delle specifiche principali

Species ReactivityHostAntibody Type
A Broad Range Of Species Rb Polyclonal Antibody

Products

Numero di catalogoConfezionamento Qtà/conf
428035-100UL Fiala di plastica 100 ul
Description
OverviewRecognizes HOCl-LDL. Weakly cross-reacts with HNE-LDL.
Catalogue Number428035
Brand Family Calbiochem®
References
ReferencesLau, B.H. 2001. J. Nutrition 131, 985s.
Product Information
FormLyophilized
FormulationUndiluted serum.
PreservativeNone
Quality LevelMQ100
Applications
Key Applications Enzyme-Linked Immunosorbent Assay
Frozen Sections
Paraffin Sections
Application NotesELISA (1:400-1:4000)
Frozen Sections (<1:400)
Paraffin Sections (<1:400)
Application CommentsDoes not cross-react with unmodified LDL. Weakly cross-reacts with HNE-LDL. Variables associated with assay conditions will dictate the optimal working dilution.
Biological Information
Immunogenhuman hypochlorite-modified low density lipoprotein (LDL)
ImmunogenHuman
HostRabbit
IsotypeIgG
Species Reactivity
  • A Broad Range Of Species
Antibody TypePolyclonal Antibody
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Blue Ice Only
Toxicity Standard Handling
Storage +2°C to +8°C
Do not freeze Ok to freeze
Special InstructionsReconstitute with 100 µl sterile distilled water. Following reconstitution, aliquot and freeze (-20°C).
Packaging Information
Transport Information
Supplemental Information
Specifications

Documentation

Anti-HOCl-Oxidized Low Density Lipoprotein Rabbit pAb MSDS

Titolo

Scheda di sicurezza (MSDS) 

Anti-HOCl-Oxidized Low Density Lipoprotein Rabbit pAb Certificati d'Analisi

TitoloNumero di lotto
428035

Riferimenti bibliografici

Panoramica delle referenze
Lau, B.H. 2001. J. Nutrition 131, 985s.
Scheda tecnica

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision06-August-2007 RFH
ApplicationELISA (1:400-1:4000)
Frozen Sections (<1:400)
Paraffin Sections (<1:400)
DescriptionRabbit polyclonal antibody supplied as lyophilized undiluted serum. Recognizes HOCL-oxidized low density lipoprotein (LDL).
BackgroundOxidation of LDL plays an important role in the initiation and progression of atherosclerosis. Arterial macrophages take up oxidized low-density lipoproteins (OxLDL), leading to cellular accumulation of cholesterol and oxysterols. OxLDL, but not native LDL, promotes vascular dysfunction by exerting direct cytotoxicity toward endothelial cells, by increasing chemotactic properties for monocytes, by transforming macrophages to foam cells via scavenger-receptors and by enhancing the proliferation of various cell types, e.g., endothelial cells, monocytes and smooth muscle cells; all of these events are recognized as contributing to atherogenesis.
HostRabbit
Immunogen speciesHuman
Immunogenhuman hypochlorite-modified low density lipoprotein (LDL)
IsotypeIgG
Speciesa broad range of species
FormLyophilized
FormulationUndiluted serum.
PreservativeNone
CommentsDoes not cross-react with unmodified LDL. Weakly cross-reacts with HNE-LDL. Variables associated with assay conditions will dictate the optimal working dilution.
Storage +2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsReconstitute with 100 µl sterile distilled water. Following reconstitution, aliquot and freeze (-20°C).
Toxicity Standard Handling
ReferencesLau, B.H. 2001. J. Nutrition 131, 985s.