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438190 Anti-LRP, Heavy Chain Mouse mAb (8G1)

438190
Purchase on Sigma-Aldrich

Panoramica

Replacement Information

Tabella delle specifiche principali

Species ReactivityHostAntibody Type
H M Monoclonal Antibody

Products

Numero di catalogoConfezionamento Qtà/conf
438190-100UG Bottiglia di vetro 100 μg
Description
OverviewRecognizes the ~515 kDa LRP heavy chain protein.
Catalogue Number438190
Brand Family Calbiochem®
SynonymsAnti-Low Density Lipoprotein Receptor-Related Protein
References
ReferencesMikhailenko, I., et al. 2001. J. Biol. Chem. 276, 39484.
Rebeck, W.G., et al. 2001. Mol. Brain Res. 87, 238.
Strickland, D.K., et al. 1990. J. Biol. Chem. 265, 17401.
Product Information
FormLiquid
FormulationIn 100 mM NaCl, 50 mM phosphate buffer, pH 7.4.
PreservativeNone
Quality LevelMQ100
Applications
Key Applications Immunoprecipitation
Neutralization Studies
Paraffin Sections
Enzyme-Linked Immunosorbent Assay
Flow Cytometry
Immunoblotting (Western Blotting)
Application NotesELISA (see comments)
Flow Cytometry (see comments)
Immunoblotting (1-5 µg/ml)
Immunoprecipitation (see comments)
Paraffin Sections (1-10 µg/ml)
Neutralization Studies (see comments)
Application CommentsRecognizes the low density heavy chain (~515 kDa) by immunoblotting under non-reducing conditions. This antibody has also been reported to work for immunoprecipitation, flow cytometry, and ELISA. Variables associated with assay conditions will dictate the proper working dilution.
Biological Information
Immunogennative LRP from human placenta
ImmunogenHuman
Clone8G1
HostMouse
IsotypeIgG₁
Species Reactivity
  • Human
Antibody TypeMonoclonal Antibody
Concentration Label Please refer to vial label for lot-specific concentration
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Dry Ice Only
Toxicity Standard Handling
Storage -20°C
Avoid freeze/thaw Avoid freeze/thaw
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
Packaging Information
Transport Information
Supplemental Information
Specifications

Documentation

Anti-LRP, Heavy Chain Mouse mAb (8G1) MSDS

Titolo

Scheda di sicurezza (MSDS) 

Anti-LRP, Heavy Chain Mouse mAb (8G1) Certificati d'Analisi

TitoloNumero di lotto
438190

Riferimenti bibliografici

Panoramica delle referenze
Mikhailenko, I., et al. 2001. J. Biol. Chem. 276, 39484.
Rebeck, W.G., et al. 2001. Mol. Brain Res. 87, 238.
Strickland, D.K., et al. 1990. J. Biol. Chem. 265, 17401.
Scheda tecnica

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision07-August-2007 RFH
SynonymsAnti-Low Density Lipoprotein Receptor-Related Protein
ApplicationELISA (see comments)
Flow Cytometry (see comments)
Immunoblotting (1-5 µg/ml)
Immunoprecipitation (see comments)
Paraffin Sections (1-10 µg/ml)
Neutralization Studies (see comments)
DescriptionPurified mouse monoclonal antibody. Recognizes the ~515 kDa LRP heavy chain protein.
BackgroundInhibits the binding of LRP (Low Density Lipoprotein Receptor-Related Protein) to α2-macroglobulin. LRP contributes to the pathology of Alzheimer's disease by influencing both the production and clearance of the β-amyloid peptide.
HostMouse
Immunogen speciesHuman
Immunogennative LRP from human placenta
Clone8G1
IsotypeIgG₁
Specieshuman
FormLiquid
FormulationIn 100 mM NaCl, 50 mM phosphate buffer, pH 7.4.
Concentration Label Please refer to vial label for lot-specific concentration
PreservativeNone
CommentsRecognizes the low density heavy chain (~515 kDa) by immunoblotting under non-reducing conditions. This antibody has also been reported to work for immunoprecipitation, flow cytometry, and ELISA. Variables associated with assay conditions will dictate the proper working dilution.
Storage -20°C
Avoid freeze/thaw
Do Not Freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
Toxicity Standard Handling
ReferencesMikhailenko, I., et al. 2001. J. Biol. Chem. 276, 39484.
Rebeck, W.G., et al. 2001. Mol. Brain Res. 87, 238.
Strickland, D.K., et al. 1990. J. Biol. Chem. 265, 17401.