1.52022
Chromolith® HighResolution RP-18 endcapped (monolithic) HPLC Columns
L × I.D. 100 mm x 4.6 mm HPLC Column
Sinonimo/i:
Chromolith® HighResolution RP-18 endcapped 100-4.6 HPLC column
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Informazioni su questo articolo
$1,160.00
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Product Name
Chromolith® HighResolution RP-18 endcapped, L × I.D. 100 mm x 4.6 mm HPLC column
Materiali
PEEK column
Livello qualitativo
agenzia
suitable for USP L1
Nome Commerciale
Chromolith®
Caratteristiche
endcapped
endcapped
Confezionamento
1 ea of
Grado di funzionalizzazione
15% Carbon loading
18% Carbon loading
Parametri
200 bar pressure
200 bar pressure
45 °C max. temp.
50 °C max. temp.
tecniche
HPLC: suitable
HPLC: suitable
LC/MS: suitable
mass spectrometry (MS): suitable (High)
mass spectrometry (MS): suitable (High)
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Questo articolo | 1.52020 | 1.52023 | 1.52021 |
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matrix active group C18 bonding phase, octadecylsilane (ODS) | matrix active group C18 bonding phase, octadecylsilane (ODS) | matrix active group C18 bonding phase, octadecylsilane (ODS) | matrix active group C18 bonding phase, octadecylsilane (ODS) |
separation technique reversed phase | separation technique reversed phase | separation technique reversed phase | separation technique reversed phase |
product line Chromolith® | product line Chromolith® | product line Chromolith® | product line Chromolith® |
pore size 1.15 μm macroporosity, 15 nm mesoporosity, 1.5 μm macroporosity | pore size 1.15 μm macroporosity, 1.5 μm macroporosity, 15 nm mesoporosity | pore size 1.15 μm macroporosity, 1.5 μm macroporosity, 15 nm mesoporosity | pore size 1.15 μm macroporosity, 1.5 μm macroporosity, 15 nm mesoporosity |
matrix highly porous, monolithic silica | matrix highly porous, monolithic silica | matrix highly porous, monolithic silica | matrix highly porous, monolithic silica |
agency suitable for USP L1 | agency suitable for ISO/CEN 6304.09, suitable for USP L1 | agency suitable for USP L1 | agency suitable for USP L1 |
Descrizione generale
Chromolith® HighResolution RP-18 endcapped columns have macropores with 1.15 μm diameter, giving a column efficiency exceeding 140,000 plates/meter. The mesopores are 15 nm (150 Å), the surface modification is octadecylsilane with full end-capping. Chromolith® HighResolution RP-18 endcapped columns fall under the USP L1 Classification. The column efficiency is comparable to a 2.7 to 3 μm particle size fully porous particulate column. Chromolith® HighResolution RP-18 endcapped columns are perfectly suitable for LC-MS applications.
The column dimension of 100 mm length and 4.6 mm I.D. is the best choice for high resolution separations of complex compound mixtures on any HPLC System.
The revolutionary, monolithic silica with its unique combination of macropores and mesopores enables:
—Rapid separations at very low column back-pressure
—High matrix tolerance, allowing time and cost savings with simplified workflows
—Cost-savings due to extended column lifetimes
—Connection of columns, flow gradients and the use of mobile phases with higher viscosity
Chromolith® HighResolution RP-18 endcapped 5-4.6 guard cartridges (3 pieces) [1.52025] with the Chromolith® Guard Cartridge Holder 5 mm x 4.6 mm [1.52032]
The Chromolith® column coupler can be used to significantly increase the separation efficiency of Chromolith® columns by coupling several columns in series (up to 100,000 plates/per column). [1.51467]
Learn more:
Brochure: Race through your Separations on Any System. Chromolith® Monolithic Silica HPLC Columns
All Supelco HPLC Columns, including monolithic Chromolith® columns, are fully compatible to all HPLC and UHPLC Instruments.
Supelco HPLC Products: The Best Choice for Any LC Instrument
Chromolith® HighResolution RP-18 endcapped columns are also available in 2 mm I.D. column dimension for perfect fit to UHPLC and UHPLC-MS needs.
Flyer: UHPLC-like performance - Rapid and Robust at Low Pressure - Chromolith® HighResolution RP-18 endcapped 2 mm I.D. HPLC Columns
Applicazioni
- A Novel and Sensitive LC-MS/MS Method for the Quantitation of Ceftiofur in Pharmaceutical Preparations and Milk Samples.: This study, conducted by Levent et al., introduces a highly sensitive LC-MS/MS method for quantifying ceftiofur in pharmaceutical preparations and milk samples. The method utilizes Chromolith® HighResolution RP-18 endcapped columns, showcasing their application in enhancing the resolution and sensitivity of chromatographic analysis in complex matrices (Levent et al., 2021).
Risultati analitici
Pressure: 40 - 70 bar
stability testing: passes test
Performance (anthracene)
Theoretical Plates (N/m) (Anthracene): ≥ 140000
Capacity factor (Anthracene): 3.9 - 4.6
Tailing (USP): 0.90 - 1.30 %
Selectivity
separation factor (anthracene/progesterone): 1.95 - 2.35
Note legali
Prodotti correlati
Codice della classe di stoccaggio
11 - Combustible Solids
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Articoli
HPLC-UV determination of 5-HMF (5-(hydroxymethyl)furfural) in beer samples using monolithic silica Chromolith® HighResolution RP-18e HPLC column.
Monolithic silica HPLC columns enable high-throughput analysis at low back pressure without loss of separation efficiency or peak capacity.
Protocolli
Folic acid vs. folate differences and biological activities; implications in fortified foods and supplements for human health.
Contenuto correlato
Small molecules are ions and compounds of molecular weight typically less than 900 daltons. These compounds can be effectively separated and analyzed by HPLC, UHPLC and LC-MS using mainly silica particles or monolithic stationary phases with a broad range of column chemistries (modifications).
Le piccole molecole sono ioni e composti di peso molecolare tipicamente inferiore a 900 dalton. Questi composti possono essere efficacemente separati e analizzati mediante HPLC, UHPLC e LC-MS utilizzando principalmente particelle di silice o fasi stazionarie monolitiche con un'ampia gamma di chimiche delle colonne (modifiche).
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Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..
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