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344845 Fumagillin, Aspergillus fumigatus - CAS 23110-15-8 - Calbiochem

344845
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Panoramica

Replacement Information

Tabella delle specifiche principali

Empirical FormulaCAS #
C₂₆H₃₄O₇ 23110-15-8

Products

Numero di catalogoConfezionamento Qtà/conf
344845-500UG Fiala di plastica 500 μg
Description
OverviewAntiprotozoal agent and angiogenesis inhibitor. Acts as an inhibitor of methionine amino-peptidase 2.
Catalogue Number344845
Brand Family Calbiochem®
SynonymsFumidil B, MetAP-2 Inhibitor I, MetAP2 Inhibitor I, Methionine Aminopeptidase 2 Inhibitor I
References
ReferencesZhang, P., et al. 2002. J. Biomed. Sci. 9, 34.
Stepien, H., et al. 1996. J. Endocrinol. 150, 99.
Abrams, J.S., et al. 1994. Cancer 74, 1164.
Jenkins, D.C., et al. 1993. Br. J. Cancer 68, 856.
Le Querrec, A., et al. 1993. Baillieres Clin. Hematol. 6, 711.
Molnar, K. 1993. Acta Vet. Hung. 41, 51.
Kusada, M., et al. 1991. Biochem. Biophys. Res. Commun. 174, 1070.
Brackett, J.M., et al. 1988. J. Agric. Food Chem. 36, 762.
Product Information
CAS number23110-15-8
ATP CompetitiveN
FormWhite to off-white powder
Hill FormulaC₂₆H₃₄O₇
Chemical formulaC₂₆H₃₄O₇
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetMethionine amino-peptidase 2
Purity≥90% by HPLC
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
RTECSHE1750000
Safety Information
R PhraseR: 22

Harmful if swallowed.
S PhraseS: 36

Wear suitable protective clothing.
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Harmful
Storage +2°C to +8°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications

Documentation

Fumagillin, Aspergillus fumigatus - CAS 23110-15-8 - Calbiochem MSDS

Titolo

Scheda di sicurezza (MSDS) 

Fumagillin, Aspergillus fumigatus - CAS 23110-15-8 - Calbiochem Certificati d'Analisi

TitoloNumero di lotto
344845

Riferimenti bibliografici

Panoramica delle referenze
Zhang, P., et al. 2002. J. Biomed. Sci. 9, 34.
Stepien, H., et al. 1996. J. Endocrinol. 150, 99.
Abrams, J.S., et al. 1994. Cancer 74, 1164.
Jenkins, D.C., et al. 1993. Br. J. Cancer 68, 856.
Le Querrec, A., et al. 1993. Baillieres Clin. Hematol. 6, 711.
Molnar, K. 1993. Acta Vet. Hung. 41, 51.
Kusada, M., et al. 1991. Biochem. Biophys. Res. Commun. 174, 1070.
Brackett, J.M., et al. 1988. J. Agric. Food Chem. 36, 762.
Scheda tecnica

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision05-July-2017 JSW
SynonymsFumidil B, MetAP-2 Inhibitor I, MetAP2 Inhibitor I, Methionine Aminopeptidase 2 Inhibitor I
DescriptionAn inhibitor of angiogenesis. Has selective cytostatic effects against ras transformed cells (IC50 = 10 pM). Antiprotozoal agent active against sporozoan parasites in bees and myxozoan parasites in fish.
FormWhite to off-white powder
Intert gas (Yes/No) Packaged under inert gas
CAS number23110-15-8
RTECSHE1750000
Chemical formulaC₂₆H₃₄O₇
Structure formulaStructure formula
Purity≥90% by HPLC
SolubilityMethanol (5 mg/ml)
Storage +2°C to +8°C
Protect from light
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
Toxicity Harmful
Merck USA index14, 4286
ReferencesZhang, P., et al. 2002. J. Biomed. Sci. 9, 34.
Stepien, H., et al. 1996. J. Endocrinol. 150, 99.
Abrams, J.S., et al. 1994. Cancer 74, 1164.
Jenkins, D.C., et al. 1993. Br. J. Cancer 68, 856.
Le Querrec, A., et al. 1993. Baillieres Clin. Hematol. 6, 711.
Molnar, K. 1993. Acta Vet. Hung. 41, 51.
Kusada, M., et al. 1991. Biochem. Biophys. Res. Commun. 174, 1070.
Brackett, J.M., et al. 1988. J. Agric. Food Chem. 36, 762.