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368620 Group III Caspase Inhibitor I - Calbiochem

368620
Purchase on Sigma-Aldrich

Panoramica

Replacement Information

Tabella delle specifiche principali

Empirical Formula
C₂₈H₃₉FN₄O₁₀

Products

Numero di catalogoConfezionamento Qtà/conf
368620-1MG Fiala di plastica 1 mg
Description
OverviewA potent, cell-permeable, and irreversible inhibitor of Group III caspases (caspase-6, -8, -9, and -10), although more effective towards caspases-6 and -8. Also inhibits caspase-1 and caspase-3. When using with purified native or recombinant enzyme, pretreatment with an esterase is required.
Catalogue Number368620
Brand Family Calbiochem®
SynonymsZ-AE(OMe)VD(OMe)-FMK
References
ReferencesGarcia-Calvo, M., et al. 1998. J. Biol. Chem. 273, 32608.
Product Information
ATP CompetitiveN
FormWhite solid
Hill FormulaC₂₈H₃₉FN₄O₁₀
Chemical formulaC₂₈H₃₉FN₄O₁₀
ReversibleN
Quality LevelMQ100
Applications
Biological Information
Primary Targetcaspase-1, caspase-3, caspase-6, caspase-8, caspase-9, caspase-10
PuritySingle spot by TLC
Physicochemical Information
Cell permeableY
Peptide SequenceZ-Ala-Glu(OMe)-Val-Asp(OMe)-CH₂F*
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Protect from Moisture Protect from moisture
Do not freeze Ok to freeze
Special InstructionsFollowing reconstituion, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications

Documentation

Group III Caspase Inhibitor I - Calbiochem MSDS

Titolo

Scheda di sicurezza (MSDS) 

Group III Caspase Inhibitor I - Calbiochem Certificati d'Analisi

TitoloNumero di lotto
368620

Riferimenti bibliografici

Panoramica delle referenze
Garcia-Calvo, M., et al. 1998. J. Biol. Chem. 273, 32608.

Brochure

Titolo
Caspases and other Apoptosis Related Tools Brochure
Scheda tecnica

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision07-July-2008 RFH
SynonymsZ-AE(OMe)VD(OMe)-FMK
DescriptionA potent, cell-permeable, and irreversible inhibitor of Group III caspases (caspases-6, -8, -9, and -10), although more effective towards caspases -6 and -8. Also inhibits caspase-1 and caspase-3. When using with purified native or recombinant enzyme, pretreatment with an esterase is required.
FormWhite solid
Chemical formulaC₂₈H₃₉FN₄O₁₀
Peptide SequenceZ-Ala-Glu(OMe)-Val-Asp(OMe)-CH₂F*
PuritySingle spot by TLC
SolubilityDMSO (20 mM)
Storage -20°C
Protect from moisture
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstituion, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesGarcia-Calvo, M., et al. 1998. J. Biol. Chem. 273, 32608.