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407621 IL-2Rα Antagonist - CAS 1217448-66-2 - Calbiochem

407621
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Panoramica

Replacement Information

Tabella delle specifiche principali

Empirical FormulaCAS #
C₂₆H₃₀N₄O₃ • CF₃CO₂H 1217448-66-2

Products

Numero di catalogoConfezionamento Qtà/conf
407621-5MG Fiala di plastica 5 mg
Description
OverviewA non-peptidyl acylphenylalanine compound that binds to IL-2 and acts as a competitive inhibitor of the IL-2/IL-2Rα interaction (IC50 = 3 µM).
Catalogue Number407621
Brand Family Calbiochem®
Synonyms(R)-N-(2-(1-(Aminoiminomethyl)-3-piperidinyl)-1-oxoethyl)-4-(phenylethynyl)-L-phenylalanine methyl ester, trifluoroacetate, Ro26-4550
References
ReferencesEmerson, S.D., et al. 2003. Protein Science 12, 811.
Tilley, J.W., et al. 1997. J. Am. Chem. Soc. 119, 7589.
Product Information
CAS number1217448-66-2
ATP CompetitiveN
FormWhite solid
Hill FormulaC₂₆H₃₀N₄O₃ • CF₃CO₂H
Chemical formulaC₂₆H₃₀N₄O₃ • CF₃CO₂H
Hygroscopic Hygroscopic
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetInhibitor of the IL-2/IL-2Rα interaction
Primary Target IC<sub>50</sub>3 µM against IL-2/IL-2Rα interaction
Purity≥95% by HPLC
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage +2°C to +8°C
Protect from Light Protect from light
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications

Documentation

IL-2Rα Antagonist - CAS 1217448-66-2 - Calbiochem MSDS

Titolo

Scheda di sicurezza (MSDS) 

IL-2Rα Antagonist - CAS 1217448-66-2 - Calbiochem Certificati d'Analisi

TitoloNumero di lotto
407621

Riferimenti bibliografici

Panoramica delle referenze
Emerson, S.D., et al. 2003. Protein Science 12, 811.
Tilley, J.W., et al. 1997. J. Am. Chem. Soc. 119, 7589.
Scheda tecnica

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision01-April-2011 RFH
Synonyms(R)-N-(2-(1-(Aminoiminomethyl)-3-piperidinyl)-1-oxoethyl)-4-(phenylethynyl)-L-phenylalanine methyl ester, trifluoroacetate, Ro26-4550
DescriptionA non-peptidyl acylphenylalanine compound that binds to IL-2 and acts as a competitive inhibitor of the IL-2/IL-2Rα interaction (IC50 = 3 µM).
FormWhite solid
Intert gas (Yes/No) Packaged under inert gas
CAS number1217448-66-2
Chemical formulaC₂₆H₃₀N₄O₃ • CF₃CO₂H
Structure formulaStructure formula
Purity≥95% by HPLC
SolubilityDMSO (28 mg/ml) or Ethanol (2 mg/ml)
Storage +2°C to +8°C
Hygroscopic
Protect from light
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Toxicity Standard Handling
ReferencesEmerson, S.D., et al. 2003. Protein Science 12, 811.
Tilley, J.W., et al. 1997. J. Am. Chem. Soc. 119, 7589.