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407252 Insulin-Like Growth Factor-I, Mouse, Recombinant, E. coli

407252
Purchase on Sigma-Aldrich

Panoramica

Replacement Information

Tabella delle specifiche principali

Purity
≥98% by SDS and HPLC

Products

Numero di catalogoConfezionamento Qtà/conf
407252-100UG Fiala di plastica 100 μg
Description
OverviewFull-length, recombinant, mouse insulin-like growth factor I (IGF-I) expressed in E. coli. IGF-I regulates proliferation and survival signals through the Akt pathway. Mouse IGF-I shares 94% sequence identity with human IGF-I and exhibits cross-species reactivity. Useful in the study of cell proliferation and survival signals.
Catalogue Number407252
Brand Family Calbiochem®
SynonymsmIGF-I
References
ReferencesClemmons, D.R., et al. 2006. Curr. Opin. in Pharmacol. 6, 620.
Bell, G.I., et al. 1986. Nucleic Acids Res. 14, 7873.
Product Information
FormLyophilized
FormulationSterile-filtered prior to lyophilization. Contains no additives.
Quality LevelMQ100
Applications
Biological Information
Biological activityED₅₀: ≤2 ng/ml (corresponding to a specific activity of ≥1 x 10⁶ units/mg) as determined by a cell proliferation assay using FDC-P1 cells. For most in vitro applications IGF-I exerts is biological activity in the concentration range of 1-20 ng/ml.
Purity≥98% by SDS and HPLC
Physicochemical Information
ContaminantsEndotoxin: ≤1 ng/µg IGF-I
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Blue Ice Only
Toxicity Standard Handling
Storage -20°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. Avoid freeze/thaw cycles of solutions. Aliquots may be stored at 4°C for up to 1 week without loss of biological activity.
Packaging Information
Transport Information
Supplemental Information
Specifications

Documentation

Insulin-Like Growth Factor-I, Mouse, Recombinant, E. coli MSDS

Titolo

Scheda di sicurezza (MSDS) 

Insulin-Like Growth Factor-I, Mouse, Recombinant, E. coli Certificati d'Analisi

TitoloNumero di lotto
407252

Riferimenti bibliografici

Panoramica delle referenze
Clemmons, D.R., et al. 2006. Curr. Opin. in Pharmacol. 6, 620.
Bell, G.I., et al. 1986. Nucleic Acids Res. 14, 7873.
Scheda tecnica

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision14-October-2008 JSW
SynonymsmIGF-I
DescriptionFull-length, recombinant, mouse insulin-like growth factor I (IGF-I) expressed in E. coli. IGF-I regulates proliferation and survival signals through the Akt pathway. Mouse IGF-I shares 94% sequence identity with human IGF-I and exhibits cross-species reactivity. Useful in the study of cell proliferation and survival signals.
FormLyophilized
FormulationSterile-filtered prior to lyophilization. Contains no additives.
Purity≥98% by SDS and HPLC
ContaminantsEndotoxin: ≤1 ng/µg IGF-I
Biological activityED₅₀: ≤2 ng/ml (corresponding to a specific activity of ≥1 x 10⁶ units/mg) as determined by a cell proliferation assay using FDC-P1 cells. For most in vitro applications IGF-I exerts is biological activity in the concentration range of 1-20 ng/ml.
SolubilityReconstitute with sterile H₂O to a final concentration of 0.1-1 mg/ml. Further dilute with aqueous buffer before use.
Storage -20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. Avoid freeze/thaw cycles of solutions. Aliquots may be stored at 4°C for up to 1 week without loss of biological activity.
Toxicity Standard Handling
ReferencesClemmons, D.R., et al. 2006. Curr. Opin. in Pharmacol. 6, 620.
Bell, G.I., et al. 1986. Nucleic Acids Res. 14, 7873.