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420131 JNK Inhibitor III, Cell-Permeable, Negative Control - Calbiochem

420131
Purchase on Sigma-Aldrich

Panoramica

Replacement Information

Tabella delle specifiche principali

Empirical Formula
C₁₉₁H₃₃₆N₇₀O₄₈S

Products

Numero di catalogoConfezionamento Qtà/conf
420131-1MG Fiala di plastica 1 mg
Description
OverviewA cell-permeable 37-mer peptide that contains a scrambled human c-Jun δ domain (amino acids 33-57) sequence linked to that of HIV-TAT protein transduction domain (amino acids 47-57) via a γ-aminobutyric acid (GABA) spacer. Does not disrupt c-Jun/JNK complex formation and thus serves as a negative control for JNK Inhibitor III, Cell-Permeable (Cat. No. 420130).
Catalogue Number420131
Brand Family Calbiochem®
SynonymsHIV-TAT₄₇₋₅₇-gaba-c-JUNδ₃₃₋₅₇, scrambled, Ac-YGRKKRRQRRR-gaba-DSNLIRGVLPTLMPKSLAQNKLKHA-NH₂
References
ReferencesHolzberg, D., et al. 2003. J. Biol. Chem. 278, 40213.
Product Information
ATP CompetitiveN
FormLyophilized white solid
FormulationSupplied as a trifluoroacetate salt.
Hill FormulaC₁₉₁H₃₃₆N₇₀O₄₈S
Chemical formulaC₁₉₁H₃₃₆N₇₀O₄₈S
Hygroscopic Hygroscopic
ReversibleN
Quality LevelMQ100
Applications
Biological Information
Primary TargetServes as a negative control for JNK Inhibitor III, Cell-Permeable (Cat. No. 420130).
Purity≥95% by HPLC
Physicochemical Information
Cell permeableY
Peptide SequenceAc-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-gaba-Asp-Ser-Asn-Leu-Ile-Arg-Gly-Val-Leu-Pro-Thr-Leu-Met-Pro-Lys-Ser-Leu-Ala-Gln-Asn-Lys-Leu-Lys-His-Ala-NH₂
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Shipped with Blue Ice or with Dry Ice
Toxicity Standard Handling
Storage -20°C
Protect from Light Protect from light
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications

Documentation

JNK Inhibitor III, Cell-Permeable, Negative Control - Calbiochem MSDS

Titolo

Scheda di sicurezza (MSDS) 

JNK Inhibitor III, Cell-Permeable, Negative Control - Calbiochem Certificati d'Analisi

TitoloNumero di lotto
420131

Riferimenti bibliografici

Panoramica delle referenze
Holzberg, D., et al. 2003. J. Biol. Chem. 278, 40213.
Scheda tecnica

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision25-July-2008 RFH
SynonymsHIV-TAT₄₇₋₅₇-gaba-c-JUNδ₃₃₋₅₇, scrambled, Ac-YGRKKRRQRRR-gaba-DSNLIRGVLPTLMPKSLAQNKLKHA-NH₂
DescriptionA cell-permeable 37 amino acid peptide that contains a scrambled sequence derived from the JNK binding domain (δ) of human c-Jun (amino acids 33-57) fused to the HIV-TAT transduction domain (amino acids 47-57) via a γ-aminobutyric acid (GABA) spacer. Does not disrupt c-Jun/JNK complex formation. Serves as a negative control for JNK Inhibitor III, Cell-Permeable (Cat. No. 420130).
FormLyophilized white solid
FormulationSupplied as a trifluoroacetate salt.
Intert gas (Yes/No) Packaged under inert gas
Chemical formulaC₁₉₁H₃₃₆N₇₀O₄₈S
Peptide SequenceAc-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-gaba-Asp-Ser-Asn-Leu-Ile-Arg-Gly-Val-Leu-Pro-Thr-Leu-Met-Pro-Lys-Ser-Leu-Ala-Gln-Asn-Lys-Leu-Lys-His-Ala-NH₂
Purity≥95% by HPLC
SolubilityDMSO (1 mg/ml)
Storage -20°C
Hygroscopic
Protect from light
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesHolzberg, D., et al. 2003. J. Biol. Chem. 278, 40213.