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475874 MK571, Sodium Salt - CAS 115104-28-4 - Calbiochem

475874
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Panoramica

Replacement Information

Tabella delle specifiche principali

Empirical FormulaCAS #
C₂₆H₂₆ClN₂O₃S₂ • Na 115104-28-4

Products

Numero di catalogoConfezionamento Qtà/conf
475874-5MG Fiala di plastica 5 mg
Description
OverviewA selective, competitive antagonist of leukotriene D4 (LTD4) (Ki = 2.1 nM for inhibition of [3H]LTD4 binding to human lung membranes). Also inhibits multidrug resistance-associated protein 1 (MRP1).
Catalogue Number475874
Brand Family Calbiochem®
SynonymsL 660711, Sodium Salt, (E)-3-[[[3-[2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-[[3-dimethylamino)-3-oxopropyl]thio]methyl]thio]-propanoic Acid, Sodium Salt
References
ReferencesOlson, D.P., et al. 2001. Cytometry 46, 105.
Van der Kolk, D.M., et al. 1998. Clin. Cancer Res. 4, 1727.
Jones, T.R., et al. 1989. Can. J. Physiol. Pharmacol. 67, 17.
Product Information
CAS number115104-28-4
ATP CompetitiveN
FormOff-white solid
Hill FormulaC₂₆H₂₆ClN₂O₃S₂ • Na
Chemical formulaC₂₆H₂₆ClN₂O₃S₂ • Na
Hygroscopic Hygroscopic
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetAntagonist of leukotriene D4 (LTD4)
Primary Target K<sub>i</sub>2.1 nM for inhibition of [3H]LTD4 binding to human lung membranes
Purity≥90% by HPLC
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Protect from Moisture Protect from moisture
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Aqueous stock solutions in are stable for up to 1 week at -20°C; DMSO stock solutions are stable for up to 6 months at -20°C. Acidic pH and heavy metals will accelerate decomposition.
Packaging Information
Transport Information
Supplemental Information
Specifications

Documentation

MK571, Sodium Salt - CAS 115104-28-4 - Calbiochem MSDS

Titolo

Scheda di sicurezza (MSDS) 

MK571, Sodium Salt - CAS 115104-28-4 - Calbiochem Certificati d'Analisi

TitoloNumero di lotto
475874

Riferimenti bibliografici

Panoramica delle referenze
Olson, D.P., et al. 2001. Cytometry 46, 105.
Van der Kolk, D.M., et al. 1998. Clin. Cancer Res. 4, 1727.
Jones, T.R., et al. 1989. Can. J. Physiol. Pharmacol. 67, 17.
Scheda tecnica

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision11-August-2008 RFH
SynonymsL 660711, Sodium Salt, (E)-3-[[[3-[2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-[[3-dimethylamino)-3-oxopropyl]thio]methyl]thio]-propanoic Acid, Sodium Salt
DescriptionA selective, competitive antagonist of leukotriene D4 (LTD4) receptor (Ki = 2.1 nM for inhibition of [3H]LTD4 binding to human lung membranes). Also reported to inhibit multidrug resistance-associated protein 1 (MRP1).
FormOff-white solid
CAS number115104-28-4
Chemical formulaC₂₆H₂₆ClN₂O₃S₂ • Na
Structure formulaStructure formula
Purity≥90% by HPLC
SolubilityH₂O (200 mg/ml) or DMSO (10 mg/ml)
Storage -20°C
Hygroscopic
Protect from moisture
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Aqueous stock solutions in are stable for up to 1 week at -20°C; DMSO stock solutions are stable for up to 6 months at -20°C. Acidic pH and heavy metals will accelerate decomposition.
Toxicity Standard Handling
ReferencesOlson, D.P., et al. 2001. Cytometry 46, 105.
Van der Kolk, D.M., et al. 1998. Clin. Cancer Res. 4, 1727.
Jones, T.R., et al. 1989. Can. J. Physiol. Pharmacol. 67, 17.