Attenzione: Ci siamo trasferiti. Non è più possibile acquistare i prodotti Merck Millipore nel sito MerckMillipore.comPer saperne di più

444244 MMP-2 Inhibitor I - CAS 10335-69-0 - Calbiochem

444244
Purchase on Sigma-Aldrich

Panoramica

Replacement Information

Tabella delle specifiche principali

Empirical FormulaCAS #
C₁₈H₃₅NO₂ 10335-69-0

Products

Numero di catalogoConfezionamento Qtà/conf
444244-10MG Fiala di plastica 10 mg
Description
OverviewA cell-permeable, potent inhibitor of MMP-2 that acts in a dose-dependent manner (Ki = 1.7 µM).
Catalogue Number444244
Brand Family Calbiochem®
Synonymscis-9-Octadecenoyl-N-hydroxylamide, Oleoyl-N-hydroxylamide, OA-Hy
References
ReferencesBerton, A., et. al. 2001. J. Biol. Chem. 276, 20458.
Emonard, H., et al. 1999. Ann. N.Y. Acad. Sci. 878, 647.
Product Information
CAS number10335-69-0
ATP CompetitiveN
FormWhite solid
Hill FormulaC₁₈H₃₅NO₂
Chemical formulaC₁₈H₃₅NO₂
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetMMP-2
Primary Target K<sub>i</sub>1.7 mM
Purity≥98% by TLC
Physicochemical Information
Cell permeableY
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Blue Ice Only
Toxicity Standard Handling
Storage -20°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsUnstable in solution; reconstitute just prior to use.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications

Documentation

MMP-2 Inhibitor I - CAS 10335-69-0 - Calbiochem MSDS

Titolo

Scheda di sicurezza (MSDS) 

MMP-2 Inhibitor I - CAS 10335-69-0 - Calbiochem Certificati d'Analisi

TitoloNumero di lotto
444244

Riferimenti bibliografici

Panoramica delle referenze
Berton, A., et. al. 2001. J. Biol. Chem. 276, 20458.
Emonard, H., et al. 1999. Ann. N.Y. Acad. Sci. 878, 647.

Citazioni

Titolo
  • Anthony R. White, et al. (2006) Degradation of the alzheimer disease amyloid -peptide by metal-dependent up-regulation of metalloprotease activity. journal of Biological Chemistry 281, 17670-17680.
  • Michelle K.Y. Siu and C. Yan Cheng. (2004) Interactions of proteases, protease inhibitors, and the β1 integrin/laminin γ3 protein complex in the regulation of ectoplasmic specialization dynamics in the rat testis. Biology of Reproduction 70, 945-964.
  • Feng Zheng, et al. (2004) Development of albuinuria and glomerular lesions in normoglycemic B6 recepients of db/db mice bone marrow. Diabetes 53, 2420-2427.
  • Scheda tecnica

    Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

    Revision03-April-2008 RFH
    Synonymscis-9-Octadecenoyl-N-hydroxylamide, Oleoyl-N-hydroxylamide, OA-Hy
    DescriptionPotent inhibitor of MMP-2 (gelatinase A). Inhibits MMP-2 in a dose dependent manner (Ki = 1.7 µM)
    FormWhite solid
    Intert gas (Yes/No) Packaged under inert gas
    CAS number10335-69-0
    Chemical formulaC₁₈H₃₅NO₂
    Structure formulaStructure formula
    Purity≥98% by TLC
    SolubilityDMSO (2 mg/ml) or Ethanol (3 mg/ml)
    Storage -20°C
    Protect from light
    Do Not Freeze Ok to freeze
    Special InstructionsUnstable in solution; reconstitute just prior to use.
    Toxicity Standard Handling
    ReferencesBerton, A., et. al. 2001. J. Biol. Chem. 276, 20458.
    Emonard, H., et al. 1999. Ann. N.Y. Acad. Sci. 878, 647.
    Citation
  • Anthony R. White, et al. (2006) Degradation of the alzheimer disease amyloid -peptide by metal-dependent up-regulation of metalloprotease activity. journal of Biological Chemistry 281, 17670-17680.
  • Michelle K.Y. Siu and C. Yan Cheng. (2004) Interactions of proteases, protease inhibitors, and the β1 integrin/laminin γ3 protein complex in the regulation of ectoplasmic specialization dynamics in the rat testis. Biology of Reproduction 70, 945-964.
  • Feng Zheng, et al. (2004) Development of albuinuria and glomerular lesions in normoglycemic B6 recepients of db/db mice bone marrow. Diabetes 53, 2420-2427.