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5.05772

Pirenzepine Dihydrochloride

Synonym(s):

Pirenzepine Dihydrochloride, Muscarinic Acetylcholine Receptor (mAChR) M1 Antagonist, Pirenzepine dihydrochloride

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About This Item

Empirical Formula (Hill Notation):
C19H21N5O2 · 2HCl
CAS Number:
28797-61-7
Molecular Weight:
424.32
MDL number:
MFCD00242717
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥99% (HPLC)
Form:
solid
Storage condition:
OK to freeze, protect from light
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assay

≥99% (HPLC)

Quality Segment

100

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, protect from light

color

white

solubility

water: 100 mM

storage temp.

2-8°C

SMILES string

N4(CCN(CC4)C)CC(=O)[n]1c2ncccc2[nH][c](c3c1cccc3)=O

InChI

1S/C19H21N5O2/c1-22-9-11-23(12-10-22)13-17(25)24-16-7-3-2-5-14(16)19(26)21-15-6-4-8-20-18(15)24/h2-8H,9-13H2,1H3,(H,21,26)

InChI key

RMHMFHUVIITRHF-UHFFFAOYSA-N

General description

An antagonist selective for mAChR subtype M1. Used for studying the functional roles of M1 receptors in both central and peripheral nervous systems.

Biochem/physiol Actions

Primary Target
M1

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Shirey, K., et al., 2009. J. Neurosci.29, 14271.
Pelat, M., et al., 1999. Eur.J. Pharmacol.379, 117.
Burford NT, et al. 1996. Biochem. J.315, 883.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

5057720001: + 5057720002:

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Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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