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07-2274

Anti-FSP1/S100A4 Antibody

from rabbit

Synonym(s):

S100 calcium binding protein A4, S100 calcium-binding protein A4, fibroblast-specific protein-1, leukemia multidrug resistance associated protein, S100 calcium binding protein A4 (calcium protein, calvasculin, metastasin, murine placental homolog), malig

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About This Item

eCl@ss:
32160702
UNSPSC Code:
12352203
NACRES:
NA.41
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IHC, WB
Citations:
11
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biological source

rabbit

Quality Segment

100

conjugate

unconjugated

antibody product type

primary antibodies

clone

polyclonal

species reactivity

mouse, human

technique(s)

immunohistochemistry: suitable (paraffin), western blot: suitable

isotype

IgG

NCBI accession no.

NP_035441

UniProt accession no.

P07091

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... S100A4(6275)
mouse ... S100A4(20198)

General description

Fibroblast-specific protein-1 (FSP1)/S100A4 is a cytoplasmic calcium-binding protein belonging to the S100 superfamily of which at least 21 members have been identified so far. Researchers believe that FSP1/S1004A is highly expressed in fibroblasts (Iwano et al., 2001; Strutz et al., 1995), in epithelial and endothelial cells undergoing epithelial-mesenchymal transition (EMT) (Iwano et al., 2002; Zeisberg and Neilson, 2009), and epithelial cancer cells that complete a transition to a metastatic phenotype (Xue et al., 2003).
~ 12 kDa

Immunogen

Epitope: Unknown
Histidine-tagged recombinant protein corresponding to mouse FSP1/S100-A4.

Application

Detect the FSP1/S100A4 protein using this Anti-FSP1/S100A4 validated for use in WB & IHC.
Research Category
Signaling
Research Sub Category
GPCR, cAMP/cGMP & Calcium Signaling
Western Blot Analysis: 1 µg/mL from a previous lot detected S100-A4 on 10 µg of HeLa cell lysate.

Physical form

Format: Purified
Protein G Purified
Purified rabbit polyclonal containing PBS with 0.05% sodium azide.

Preparation Note

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Control
NIH/3T3 cell lysate
Evaluated by Western Blot in NIH/3T3 cell lysate.

Western Blot Analysis: 1 µg/mL of this antibody detected FSP1/S100-A4 on 10 µg of NIH/3T3 cell lysate.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

07-2274:

jan

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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