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ABC244 Anti-PATE1 Antibody

This Anti-PATE1 Antibody is validated for use in Western Blotting and Immunohistochemistry (Paraffin) for the detection of PATE1.

Anti-PATE1 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Apoptosis & Cancer Research Sub-Category: Apoptosis - Additional Gene Symbol: PATE1, PATE UniProt Number: Q8WXA2
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ABC244
100 µL  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, RWB, IH(P)RbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABC244
      DescriptionAnti-PATE1 Antibody
      Alternate Names
      • Prostate and testis expressed protein 1
      Background InformationPATE1 is a secreted protein that is expressed exclusively in the prostate and testis and is up regulated in the prostate epithelial cells during cancer. Because of the extreme specificity of PATE1 expression it makes it a potential target for immunotherapy in prostate cancer. PATE1 is the founding member of new syntenic loci in humans and mice that encode secreted proteins that have 10 cysteine residues. The PATE family has three-fingered protein/Ly-6/urokinase-type plasminogen activator receptor (uPAR) domains that shape three-fingered proteins (TFPs). Additional members include PATE-M, PATE-DJ, and PATE-B that are also expressed in prostate and testis and sperm. Related proteins, PATE-P and PATE-Q are expressed only in placenta. Research indicates that PATE proteins may have something to do with fertility and recent research showed that addition PATE-like genes were expressed in neuron-rich tissues and thus may have a role in neurological function or transmission.
      References
      Product Information
      FormatAffinity Purified
      PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationThis Anti-PATE1 Antibody is validated for use in Western Blotting and Immunohistochemistry (Paraffin) for the detection of PATE1.
      Key Applications
      • Western Blotting
      • Immunohistochemistry (Paraffin)
      Application NotesImmunohistochemistry Analysis: A 1:50 dilution from a representative lot detected PATE1 in human testis and human hyperplastic prostate tissue.
      Biological Information
      ImmunogenGST-tagged recombinant protein corresponding to human PATE1.
      ConcentrationPlease refer to lot specific datasheet.
      HostRabbit
      Species Reactivity
      • Human
      • Rat
      Species Reactivity NoteHuman, Rat. Predicted to react with mouse based on 70% sequence homology.
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • PATE1
      • PATE
      Purification MethodAffinity Purfied
      UniProt Number
      Molecular Weight~14 kDa observed
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in rat testis tissue lysate.

      Western Blotting Analysis: A 1:500 dilution of this antibody detected PATE1 in 10 µg of rat testis tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      ABC244 04053252986406

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies