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220411 Chenodeoxycholic Acid, Sodium Salt - CAS 2646-38-0 - Calbiochem

Bile acid that has been shown to increase intracellular Ca2+ in isolated rat hepatocyte couplets. Induces a permeability transition in freshly isolated rat liver mitochondria.

Chenodeoxycholic Acid, Sodium Salt - CAS 2646-38-0 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
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220411
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
2646-38-0C₂₄H₃₉O₄ · Na

Pricing & Availability

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220411-100GMCN
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      220411-5GMCN
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          Description
          OverviewBile acid that has been shown to increase intracellular Ca2+ in isolated rat hepatocyte couplets. Induces a permeability transition in freshly isolated rat liver mitochondria.
          Catalogue Number220411
          Brand Family Calbiochem®
          References
          ReferencesRolo, A.P., et al. 2001. Biosci. Rep. 21, 73.
          Thibault, N., and Ballet, F. 1993. Biochem. Pharmacol. 45, 289.
          Roda, A., et al. 1990. J. Lipid Res. 31, 1433.
          Spivak, W., et al. 1988. Biochem. J. 252, 275.
          Hisadome, T., et al. 1980. Gastroenterol. Jpn. 15, 257.
          Product Information
          CAS number2646-38-0
          FormWhite solid
          Hill FormulaC₂₄H₃₉O₄ · Na
          Chemical formulaC₂₄H₃₉O₄ · Na
          Hygroscopic Hygroscopic
          Structure formula ImageStructure formula Image
          Quality LevelMQ100
          Applications
          Biological Information
          Purity>95% by TLC
          Physicochemical Information
          Heavy metals<10 ppm
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          RTECSFZ2231000
          Safety Information
          R PhraseR: 20/21/22-40

          Harmful by inhalation, in contact with skin and if swallowed.
          Limited evidence of a carcinogenic effect.
          S PhraseS: 22-36-53

          Do not breathe dust.
          Wear suitable protective clothing.
          Avoid exposure - obtain special instructions before use.
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Harmful & Carcinogenic / Teratogenic
          Storage +15°C to +30°C
          Hygroscopic Hygroscopic
          Do not freeze Ok to freeze
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications
          Global Trade Item Number
          Catalogue Number GTIN
          220411-100GMCN 04055977201079
          220411-5GMCN 04055977201093

          Documentation

          Chenodeoxycholic Acid, Sodium Salt - CAS 2646-38-0 - Calbiochem SDS

          Title

          Safety Data Sheet (SDS) 

          Chenodeoxycholic Acid, Sodium Salt - CAS 2646-38-0 - Calbiochem Certificates of Analysis

          TitleLot Number
          220411

          References

          Reference overview
          Rolo, A.P., et al. 2001. Biosci. Rep. 21, 73.
          Thibault, N., and Ballet, F. 1993. Biochem. Pharmacol. 45, 289.
          Roda, A., et al. 1990. J. Lipid Res. 31, 1433.
          Spivak, W., et al. 1988. Biochem. J. 252, 275.
          Hisadome, T., et al. 1980. Gastroenterol. Jpn. 15, 257.

          Brochure

          Title
          Biological Detergents Brochure
          Bulk Product Guide
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision28-April-2008 RFH
          DescriptionBile acid that has been shown to increase intracellular Ca2+ in isolated rat hepatocyte couplets.
          FormWhite solid
          CAS number2646-38-0
          RTECSFZ2231000
          Chemical formulaC₂₄H₃₉O₄ · Na
          Structure formulaStructure formula
          Purity>95% by TLC
          SolubilityAqueous buffers or H₂O (20 mg/ml)
          Storage +15°C to +30°C
          Hygroscopic
          Do Not Freeze Ok to freeze
          Toxicity Harmful & Carcinogenic / Teratogenic
          Merck USA index14, 2054
          ReferencesRolo, A.P., et al. 2001. Biosci. Rep. 21, 73.
          Thibault, N., and Ballet, F. 1993. Biochem. Pharmacol. 45, 289.
          Roda, A., et al. 1990. J. Lipid Res. 31, 1433.
          Spivak, W., et al. 1988. Biochem. J. 252, 275.
          Hisadome, T., et al. 1980. Gastroenterol. Jpn. 15, 257.