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Merck

19-142

LY 294002

Synonym(s):

NSC 697286, PI3K inhibitor, SF 1101

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About This Item

UNSPSC Code:
12352202
NACRES:
NA.41
eCl@ss:
32160405
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form

solid

Quality Level

manufacturer/tradename

Upstate®

technique(s)

activity assay: suitable (kinase)

shipped in

wet ice

Application

Specific and potent inhibitor of PI 3-kinase.

Biochem/physiol Actions

Inhibitor Type: Kinase

Physical form

C19H17NO3

Preparation Note

2 years at -20°C

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

487.4 °F

flash_point_c

253.0 °C


Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

19-142:

jan



Certificates of Analysis (COA)

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Wen Jiang et al.
Bioengineered, 12(2), 10264-10284 (2021-11-02)
Chronic skin ulcers are a primary global health problem. Velvet antler polypeptide (VAP) regulates endothelial cell migration and angiogenic sprout. Adipose-derived stem cells (ADSCs) are reported to make pivotal impacts upon wound healing. This study aimed to explore the role
C J Vlahos et al.
The Journal of biological chemistry, 269(7), 5241-5248 (1994-02-18)
Phosphatidylinositol (PtdIns) 3-kinase is an enzyme implicated in growth factor signal transduction by associating with receptor and nonreceptor tyrosine kinases, including the platelet-derived growth factor receptor. Inhibitors of PtdIns 3-kinase could potentially give a better understanding of the function and
Shang Li et al.
NPJ biofilms and microbiomes, 9(1), 47-47 (2023-07-09)
Knowledge gaps that limit the development of therapies for polycystic ovary syndrome (PCOS) concern various environmental factors that impact clinical characteristics. Circadian dysrhythmia contributes to glycometabolic and reproductive hallmarks of PCOS. Here, we illustrated the amelioration of Limosilactobacillus reuteri (L.



Global Trade Item Number

SKUGTIN
19-14204053252283116