5.05313
Hexamethonium Bromide
Synonym(s):
Hexamethonium Bromide, Hexane-1,6-bis(trimethylammonium bromide), Nicotinic Acetylcholine Receptors (nAChRs) Antagonist, Hexamethonium Bromide
Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
About This Item
Empirical Formula (Hill Notation):
C12H30Br2N2
CAS Number:
Molecular Weight:
362.19
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (TLC)
Form:
powder
Storage condition:
OK to freeze, protect from light
assay
≥98% (TLC)
Quality Segment
form
powder
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, protect from light
color
white
solubility
H2O: 100 mg/mL
storage temp.
10-30°C
InChI
1S/C12H30N2.2BrH/c1-13(2,3)11-9-7-8-10-12-14(4,5)6;;/h7-12H2,1-6H3;2*1H/q+2;;/p-2
InChI key
FAPSXSAPXXJTOU-UHFFFAOYSA-L
General description
A potent antagonist of nicotinic acetylcholine receptors (nAChRs) at pre-ganglionic sites in both the sympathetic and parasympathetic nervous systems. Often used for studying the roles of nicotinic receptors in regulating cardiovascular system.
Biochem/physiol Actions
Primary Target
nAChR
nAChR
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Other Notes
Dasgupta, X., et al., 2010. Proc. Natl. Acad. Sci.103, 6332.
Karavaev, N., et al., 2008. Neurosci. Behav. Physiol.38, 297.
Nelson, E., 1999. J. Physiol.516, 657.
Christ, D. 1980. Br. J. Pharmacol.69, 249.
Karavaev, N., et al., 2008. Neurosci. Behav. Physiol.38, 297.
Nelson, E., 1999. J. Physiol.516, 657.
Christ, D. 1980. Br. J. Pharmacol.69, 249.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
Still not finding the right product?
Explore all of our products under Hexamethonium Bromide
Storage Class
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.