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5.05412

1,1-Dimethyl-4-phenylpiperazinium iodide

Name: 1,1-Dimethyl-4-phenylpiperazinium iodide
Brand: MM

Synonym(s):

1,1-Dimethyl-4-phenylpiperazinium iodide, 1,1-dimethyl-4-phenylpiperazinium, Nicotinic Acetylcholine Receptor (nAChR) Agonist, DMPP, (α3)2(β4)3 Nicotinic Acetylcholine Receptor (nAChR) Agonist, DMPP, Ganglionic Nicotinic Acetylcholine Receptor (nAChR) Agonist, DMPP

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About This Item

Empirical Formula (Hill Notation):

C₁₂H₁₉IN₂

CAS Number:

54-77-3

Molecular Weight:

318.20

UNSPSC Code:

12352200

MDL number:

MFCD00011976

Assay:

≥98% (titration)

Form:

powder

Storage condition:

OK to freeze, protect from light

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Properties

assay

≥98% (titration)

Quality Segment

100

form

powder

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze, protect from light

color

white

solubility

50% acetic acid: 50 mg/mL

storage temp.

2-8°C

InChI

1S/C12H19N2.HI/c1-14(2)10-8-13(9-11-14)12-6-4-3-5-7-12;/h3-7H,8-11H2,1-2H3;1H/q+1;/p-1

InChI key

XFZJGFIKQCCLGK-UHFFFAOYSA-M

Description

General description

An agonist selective for ganglionic subtype of acetylcholine receptors (nAChR) and acts as a ganglionic stimulant. At higher concentrations also inhibits the uptake of NE and 5-HT.

Biochem/physiol Actions

Primary Target
nAChR

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Chen, R., et al., 1951. J. Pharmacol. Exp. Ther. 103.
Vizi, S., 1999. Brain Res. Brain Res. Rev.30, 219.
Prado. W., et al. 2004. Brain Res.1018, 272.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c