5.05897
(±)-PD 128907 Hydrochloride - CAS 112960-16-4 - Calbiochem
Synonym(s):
(±)-PD 128907 Hydrochloride - CAS 112960-16-4 - Calbiochem
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About This Item
Empirical Formula (Hill Notation):
C14H19NO3 · xHCl
CAS Number:
Molecular Weight:
249.31 (free base basis)
UNSPSC Code:
12352200
MDL number:
assay
≥98% (HPLC)
form
powder
potency
2.3 nM Ki
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, protect from light
color
white
solubility
water: 5 mg/mL
storage temp.
−20°C
General description
Selective dopamine D3 receptor agonist (Ki = 2.3 nM) with an 18-fold selectivity over long dopamine receptors (D2L) and exhibited only weak affinity for D4.2 receptors (Ki = 169 nM). Commonly used to reproduce cocaine′s discriminative stimulus effects and also in peripheral systemic studies of hypertension.
Biochem/physiol Actions
Primary Target
D₃
D₃
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Other Notes
Achat-Mendes, c. et al. 2010. J. Pharmacol. Exp. Ther.334, 556.
Zeng, C. et al. 2006. Circul. Res.99, 494.
Pugsley, T. A. et al. 1995. J. Pharmacol. Exp. Ther.275, 1355.
Zeng, C. et al. 2006. Circul. Res.99, 494.
Pugsley, T. A. et al. 1995. J. Pharmacol. Exp. Ther.275, 1355.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
Certificates of Analysis (COA)
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