5.06044
Muscimol
≥99% (HPLC), GABAA receptor agonist, solid
동의어(들):
Muscimol, GABA A Receptor Agonist, Muscimol, GABAA Receptor Agonist, Muscimol
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크기 선택
보기 변경
제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C4H6N2O2
CAS 번호:
Molecular Weight:
114.10
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥99% (HPLC)
Form:
solid
Storage condition:
OK to freeze, protect from light
제품 이름
Muscimol,
assay
≥99% (HPLC)
Quality Segment
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, protect from light
color
white
solubility
water: 100 mM
storage temp.
2-8°C
SMILES string
[N+H3]Cc1[o]nc(c1)[O-]
InChI
1S/C4H6N2O2/c5-2-3-1-4(7)6-8-3/h1H,2,5H2,(H,6,7)
InChI key
ZJQHPWUVQPJPQT-UHFFFAOYSA-N
General description
A constituent and psychoactive ingredient of the mushroom Amanita muscariathat acts as a potent agonist of GABAA receptors (EC50 = 28 µM and 33 µM in neonatal and adult rats, respectively), with preferential efficacy and selectivity to high-affinity receptor subtypes. Shown to be permeate the blood-brain barrier. Impairs associate and memory functions.
Biochem/physiol Actions
Primary Target
GABAA
GABAA
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Other Notes
Chandra, D., et al. 2010. Neuropsychopharmacology.35, 999.
Fischer, H., et al. 2005. J. Physiol.564, 465.
Ramirez, D.R., et al. 2005. Neurobiol. Learning and Memory.84, 184.
Fischer, H., et al. 2005. J. Physiol.564, 465.
Ramirez, D.R., et al. 2005. Neurobiol. Learning and Memory.84, 184.
Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Toxic (F)
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Danger
Hazard Classifications
Acute Tox. 2 Oral - STOT SE 3
target_organs
Central nervous system
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
hcodes
저장 등급
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
시험 성적서(COA)
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