MILLIPLEX^® Non-Human Primate Metabolic Panel

Metabolic hormones such as amylin, C-peptide, ghrelin, GIP, GLP-1, glucagon, insulin, leptin, pancreatic polypeptide (PP), and PYY are central to regulating energy balance, appetite, and glucose metabolism in non-human primates. Amylin complements insulin in controlling blood glucose, while C-peptide reflects endogenous insulin production. Ghrelin stimulates hunger, and GLP-1 and GIP enhance insulin secretion post-meal. Glucagon raises blood glucose levels, and leptin signals satiety. PP and PYY modulate digestive processes and appetite. IL-6 and MCP-1/CCL2 provide insight into inflammation and immune-metabolic interactions. Together, these biomarkers offer a comprehensive view of metabolic health and endocrine function in preclinical primate models.

MILLIPLEX^® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze 12 analytes in non-human primate serum, plasma, or cell culture supernatants.

Analytes included: Amylin (active), C-Peptide, Ghrelin (active), GIP (total), GLP-1 (active), Glucagon, IL-6, Insulin, Leptin, MCP-1/CCL2, Pancreatic Polypeptide (PP), PYY (total)
Note: Some analytes require a protease inhibitor during sample collection.

Assay Characteristics: Refer to assay protocol for details on cross-reactivity, sensitivity, precision, and accuracy.

Features:

• Targets key metabolic hormones and inflammatory markers relevant to energy regulation and glucose metabolism
• Includes 12 analytes covering appetite control, insulin dynamics, and immune-metabolic signaling
• Multiplex format enables simultaneous detection from minimal sample volume
• Compatible with non-human primate serum, plasma, and tissue culture supernatant samples
• Designed for metabolic, obesity, diabetes, and inflammation research in primate models

Benefits:

• Provides a comprehensive profile of endocrine and metabolic function in non-human primates
• Supports evaluation of therapeutic interventions targeting appetite, insulin sensitivity, and inflammation
• Facilitates monitoring of hormonal responses to dietary, pharmacological, or genetic manipulations
• Enhances understanding of metabolic disease mechanisms in translational research
• Streamlines experimental workflows with high-throughput, multi-analyte capability

Luminex is a registered trademark of Luminex Corporation

MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany

xMAP is a registered trademark of Luminex Corp

For research use only. Not for use in diagnostic procedures.

Label License/Sticker for Assay Product:

By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.