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SML0060

NB001

≥98% (HPLC)

Synonym(s):

5-[[2-(6-Amino-9H-purin-9-yl)ethyl]amino]-1-pentanol; HTS 09836

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About This Item

Empirical Formula (Hill Notation):
C12H20N6O
CAS Number:
686301-48-4
Molecular Weight:
264.33
NACRES:
NA.77
PubChem Substance ID:
329825126
UNSPSC Code:
41106305
MDL number:
MFCD03086724
Assay:
≥98% (HPLC)
Form:
powder
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Quality Segment

100

assay

≥98% (HPLC)

form

powder

color

white to tan

solubility

H2O: ≥24 mg/mL

storage temp.

−20°C

SMILES string

Nc1ncnc2n(CCNCCCCCO)cnc12

InChI

1S/C12H20N6O/c13-11-10-12(16-8-15-11)18(9-17-10)6-5-14-4-2-1-3-7-19/h8-9,14,19H,1-7H2,(H2,13,15,16)

InChI key

CVPTTZZCRDVGSU-UHFFFAOYSA-N

Application

NB001 may be used in adenylyl cyclase 1-mediated cell signaling studies.

Biochem/physiol Actions

NB001, originally believed to be a selective inhibitor of adenylyl cyclase 1 (AC1), new evidence suggests NB001 does not interact with AC1 directly. NB001 may reduce cAMP accumulation in cells through an unknown mechanism that is dependent on AC1.

Features and Benefits

This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the Adenylyl cyclases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

pictograms

Skull and crossbones
GHS06

signalword

Danger

hcodes

H301

Hazard Classifications

Acute Tox. 3 Oral

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

SML0060-25MG: + SML0060-5MG: + SML0060-VAR: + SML0060-BULK:

jan

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