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Merck

KCNA2

potassium voltage-gated channel, shaker-related subfamily, member 2

동의어:
HBK5, HK4, HUKIV, KV1.2, MK2, NGK1, RBK2
:
UniProtKB ID:
Clone ID:
  • Human(3737) Summary: Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, members of which allow nerve cells to efficiently repolarize following an action potential. The coding region of this gene is intronless, and the gene is clustered with genes KCNA3 and KCNA10 on chromosome 1. [provided by RefSeq, Jul 2008]
  • Mouse(16490) potassium voltage-gated channel, shaker-related subfamily, member 2
  • Rat(25468) potassium voltage-gated channel, shaker-related subfamily, member 2
  • cow(539608) potassium voltage-gated channel, shaker-related subfamily, member 2
  • domestic cat(101083868) potassium voltage-gated channel, shaker-related subfamily, member 2
  • dog(404022) potassium voltage-gated channel, shaker-related subfamily, member 2
  • Zebrafish(100537815) potassium voltage-gated channel, shaker-related subfamily, member 2
  • chicken(395117) potassium voltage-gated channel, shaker-related subfamily, member 2
  • naked mole-rat(101717332) potassium voltage-gated channel, shaker-related subfamily, member 2
  • domestic guinea pig(100735605) potassium voltage-gated channel, shaker-related subfamily, member 2
  • sheep(101112012) potassium voltage-gated channel, shaker-related subfamily, member 2

Custom & Knockdown Gene Products

Antibodies

제품 번호
설명
종별 반응성
응용분야
ANTI-KCNA2 (C-TERM) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
종별 반응성
human
응용분야
western blot
Anti-Potassium Channel Kv1.2 Antibody, clone K14/16, clone K14/16, from mouse,
종별 반응성
rat
응용분야
immunofluorescence
immunohistochemistry

western blot
Monoclonal Anti-KCNA2 antibody produced in mouse, clone S14-16, 1 mg/mL, purified immunoglobulin,
종별 반응성
human, mouse, rat, zebrafish
응용분야
immunohistochemistry
immunoprecipitation (IP)

western blot

Small Molecule - Blocker

제품 번호
설명
Guanidine hydrochloride solution, Colorless liquid, 7.8 - 8.3 M, pH- 4.5 - 5.5,
human
Guanidine hydrochloride solution, BioUltra, ~8 M in H2O,
human
Guanidine hydrochloride, anhydrous, free-flowing, Redi-Dri, ≥99%,
human
Guanidine hydrochloride, ≥98%,
human
Dalfampridine, United States Pharmacopeia (USP) Reference Standard,
human

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human KCNA2,
human
MISSION® esiRNA, targeting mouse Kcna2,
mouse