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MABE983 Anti-Prohibitin Antibody, clone 2E12

MABE983
100 µg  
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      概要

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      主要スペック表

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H ICC, FC, IP M Purified Monoclonal Antibody
      Description
      Catalogue NumberMABE983
      DescriptionAnti-Prohibitin Antibody, clone 2E12
      Alternate Names
      • Prohibitin
      Background InformationProhibitin is an inhibitor of DNA synthesis that is widely expressed across various tissues. Prohibitin influences proliferation, and may also have a role in regulating mitochondrial respiration activity and in aging. Expression levels of prohibitin in fibroblasts have been found to decrease heterogeneously as cellular aging occurs.
      References
      Product Information
      FormatPurified
      PresentationPurified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationThis Anti-Prohibitin Antibody, clone 2E12 is validated for use in Immunocytochemistry and Flow Cytometry and Immunoprecipitation for the detection of Prohibitin.
      Key Applications
      • Immunocytochemistry
      • Flow Cytometry
      • Immunoprecipitation
      Application NotesFlow Cytometry Analysis: 1.0 µg of this antibody from a representative lot detected Prohibitin in 1X10E6 Jurkat T cells.
      Immunoprecipitation Analysis: A representative lot immunoprecipitated Prohibitin in MRC5 cells.
      Flow Cytometry Analysis: A representative lot detected Prohibitin in Jurkat cells (Thomas Moran, Mount Sinai School of Medicine, New York, NY).
      Immunocytochemistry Analysis: A representative lot detected Prohibitin in HeLa cells (Thomas Moran, Mount Sinai School of Medicine, New York, NY).
      Biological Information
      Immunogen Corresponding to human Prohibitin.
      Clone2E12
      ConcentrationPlease refer to lot specific datasheet.
      HostMouse
      IsotypeIgG2aκ
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • PHB
      Purification MethodProtein G Purified
      UniProt Number
      Molecular Weight30 kDa calculated
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Immunocytochemistry in HEK293 and NIH/3T3 cells.

      Immunocytochemistry Analysis: A 1:50 dilution of this antibody detected Prohibitin in HEK293 and NIH/3T3 cells.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications