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Merck

345860

Anti-Glial Fibrillary Acidic Protein Rat mAb (2.2B10)

liquid, clone 2.2B10, Calbiochem®

別名:

Anti-GFAP

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この商品について

NACRES:
NA.41
UNSPSC Code:
12352203
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製品名

Anti-Glial Fibrillary Acidic Protein Rat mAb (2.2B10), liquid, clone 2.2B10, Calbiochem®

biological source

rat

antibody form

purified antibody

antibody product type

primary antibodies

clone

2.2B10, monoclonal

form

liquid

contains

≤0.1% sodium azide as preservative

species reactivity

bovine, rat, mouse, human

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
avoid repeated freeze/thaw cycles

dilution

(ELISA (0.1-0.5 µg/mL)
Immunoblotting (0.1-0.5 µg/mL)
Frozen Sections (10-50 µg/mL)
Immunoprecipitation (2-5 µg/mL)
Paraffin Sections (10-50 µg/mL))

isotype

IgG2a

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

Gene Information

human ... GCM1(8521)

Analysis Note

Positive Control
Human or rat brain tissues

Application

ELISA (0.1-0.5 µg/ml)

Immunoblotting (0.1-0.5 µg/ml)

Frozen Sections (10-50 µg/ml)

Immunoprecipitation (2-5 µg/ml)

Paraffin Sections (10-50 µg/ml, see comments)

Disclaimer

Toxicity: Standard Handling (A)

General description

Purified rat monoclonal antibody. Recognizes the ~55 kDa glial fibrillary acidic protein (GFAP).
Recognizes GFAP in astrocytes induced by a variety of CNS injuries in human and rat brain tissues.
This Anti-Glial Fibrillary Acidic Protein Rat mAb (2.2B10) is validated for use in ELISA, Immunoblotting, Frozen Sections, IP, Paraffin Sections for the detection of Glial Fibrillary Acidic Protein.

Immunogen

Bovine Brain
bovine GFAP

Other Notes

Product is not to be used for animal treatment, in vivo research, or in any other contact procedure with livestock. Stains reactive rodent and human brain astrocytes induced by a variety of central nervous system injuries. This antibody is suitable for immunohistochemical staining of Bouin′s-fixed, frozen, or paraffin-embedded tissue sections. Variables associated with assay conditions will dictate the proper working dilution.
Tohyama, T., et al. 1993. Am. J. Pathol.142, 871.
Lee, V.M., et al. 1984. J. Neurochem. 42, 25.

Packaging

Please refer to vial label for lot-specific concentration.

Physical form

In PBS.

Preparation Note

Following initial thaw, aliquot and freeze (-20°C).

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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保管分類

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


試験成績書(COA)

製品のロット番号・バッチ番号を入力して、試験成績書(COA) を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。

以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

文書ライブラリにアクセスする

Michael S Petrik et al.
Neuromolecular medicine, 9(1), 83-100 (2006-11-23)
Gulf War illness (GWI) affects a significant percentage of veterans of the 1991 conflict, but its origin remains unknown. Associated with some cases of GWI are increased incidences of amyotrophic lateral sclerosis and other neurological disorders. Whereas many environmental factors
Flora Guillot et al.
Journal of neuroinflammation, 12, 130-130 (2015-07-05)
Astrocytes, the most abundant cell population in mammal central nervous system (CNS), contribute to a variety of functions including homeostasis, metabolism, synapse formation, and myelin maintenance. White matter (WM) reactive astrocytes are important players in amplifying autoimmune demyelination and may
Dorin Sade Yazdi et al.
Proceedings of the National Academy of Sciences of the United States of America, 118(24) (2021-06-09)
High levels of homocysteine are reported as a risk factor for Alzheimer's disease (AD). Correspondingly, inborn hyperhomocysteinemia is associated with an increased predisposition to the development of dementia in later stages of life. Yet, the mechanistic link between homocysteine accumulation
Ulrich F O Luhmann et al.
Human molecular genetics, 24(1), 128-141 (2014-08-26)
Understanding phenotype-genotype correlations in retinal degeneration is a major challenge. Mutations in CRB1 lead to a spectrum of autosomal recessive retinal dystrophies with variable phenotypes suggesting the influence of modifying factors. To establish the contribution of the genetic background to
Tadasuke Tominaga et al.
PloS one, 14(3), e0213673-e0213673 (2019-03-12)
Primary and secondary traumatic brain injury (TBI) can cause tissue damage by inducing cell death pathways including apoptosis, necroptosis, and autophagy. However, similar pathways can also lead to senescence. Senescent cells secrete senescence-associated secretory phenotype proteins following persistent DNA damage

関連コンテンツ

グローバルトレードアイテム番号

カタログ番号GTIN
345860-100UGCN04055977214413

ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.

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