01-0870
N-アセチル-L-システイン
SAJ special grade, 98.0-102.0%
別名:
LNAC, NAC
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この商品について
化学式:
HSCH2CH(NHCOCH3)CO2H
CAS番号:
分子量:
163.19
EC Number:
210-498-3
UNSPSC Code:
12352209
PubChem Substance ID:
Beilstein/REAXYS Number:
1724426
MDL number:
製品名
N-アセチル-L-システイン, SAJ special grade, 98.0-102.0%
InChI key
PWKSKIMOESPYIA-BYPYZUCNSA-N
InChI
1S/C5H9NO3S/c1-3(7)6-4(2-10)5(8)9/h4,10H,2H2,1H3,(H,6,7)(H,8,9)/t4-/m0/s1
SMILES string
CC(=O)N[C@@H](CS)C(O)=O
grade
SAJ special grade
assay
98.0-102.0%
form
solid
availability
available only in Japan
mp
106-108 °C (lit.)
application(s)
peptide synthesis
shipped in
wet ice
storage temp.
2-8°C
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関連するカテゴリー
Biochem/physiol Actions
抗酸化物質であり、粘液溶解薬でもあります。細胞内のフリーラジカルスカベンジャー蓄積量を増加させます。神経細胞のアポトーシスを防止する性質が報告されていますが、平滑筋細胞ではアポトーシスを誘導します。HIVの複製を阻害します。ミクロソームのグルタチオントランスフェラーゼの基質です。
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2
保管分類
13 - Non Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
I-Ta Lee et al.
The American journal of pathology, 175(2), 519-532 (2009-07-18)
Oxidative stresses are believed to play an important role in the induction of both cell adhesion molecules and pro-inflammatory cytokines, a key event in a variety of inflammatory processes. The enzyme heme oxygenase-1 (HO-1) functions as an antioxidant and serves
Eduesley Santana-Santos et al.
The Annals of thoracic surgery, 97(5), 1617-1623 (2014-03-25)
The renoprotective effect of N-acetylcystein in patients undergoing coronary artery bypass graft surgery is controversial. We assessed the renoprotective effect of the highest dose of N-acetylcystein sanctioned for clinical use in a prospective, double-blind, placebo-controlled study including 70 chronic kidney
Michael Berk et al.
Trends in pharmacological sciences, 34(3), 167-177 (2013-02-02)
N-Acetylcysteine (NAC) targets a diverse array of factors germane to the pathophysiology of multiple neuropsychiatric disorders including glutamatergic transmission, the antioxidant glutathione, neurotrophins, apoptosis, mitochondrial function, and inflammatory pathways. This review summarises the areas where the mechanisms of action of
Yuval Samuni et al.
Biochimica et biophysica acta, 1830(8), 4117-4129 (2013-04-27)
N-acetylcysteine (NAC) has been in clinical practice for several decades. It has been used as a mucolytic agent and for the treatment of numerous disorders including paracetamol intoxication, doxorubicin cardiotoxicity, ischemia-reperfusion cardiac injury, acute respiratory distress syndrome, bronchitis, chemotherapy-induced toxicity
Luigi Franchi et al.
Journal of immunology (Baltimore, Md. : 1950), 193(8), 4214-4222 (2014-09-17)
The nucleotide-binding oligomerization domain-like receptor pyrin domain-containing 3 (Nlrp3) inflammasome plays an important role in inflammation by controlling the maturation and secretion of the cytokines IL-1β and IL-18 in response to multiple stimuli including pore-forming toxins, particulate matter, and ATP.
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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