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15527

グリシン

meets analytical specification of Ph. Eur., BP, USP, 99-101% (based on anhydrous substance)

別名:

アミノエタン酸, アミノ酢酸, グリココール

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この商品について

化学式:
NH2CH2COOH
CAS番号:
56-40-6
分子量:
75.07
NACRES:
NA.21
PubChem Substance ID:
57647473
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
200-272-2
MDL number:
MFCD00008131
Beilstein/REAXYS Number:
635782
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Quality Level

200

assay

99-101% (based on anhydrous substance)

form

crystalline powder

quality

meets analytical specification of Ph. Eur., BP, USP

technique(s)

IR spectroscopy: suitable

impurities

hydrolyzable substances, complies, organic volatile impurities, complies (GC), residual solvents, complies, ≤0.001% heavy metals (as Pb), ≤1.0% ninhydrin-positive substances

ign. residue

≤0.1% (as SO4)

loss

≤0.2% loss on drying, 105 °C, 2 h

color

white

pH

5.9-6.4 (20 °C, 5%)

pKa (25 °C)

(1) 2.35, (2) 9.60, 2.35

mp

240 °C (dec.) (lit.)

solubility

H2O: soluble 25 gm in 100 ml at 25 degrees c, H2O: soluble 39.1 gm in 100 ml at 50 degrees c, alcohol: soluble 0.06 gm in 100 gm (Absolute), pyridine: soluble 164 parts, alcohol: very slightly soluble, diethyl ether: very slightly soluble

anion traces

chloride (Cl-): ≤50 mg/kg, sulfate (SO42-): ≤50 mg/kg

suitability

complies for appearance of solution, complies for reaction against H2SO4, in accordance for identity (IR)

SMILES string

NCC(O)=O

InChI

1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)

InChI key

DHMQDGOQFOQNFH-UHFFFAOYSA-N

Gene Information

rat ... Grin2a(24409)

Application

Glycine was used for preparing platelets from whole-blood samples and study the stimulation of cytokine expression in leukocytes. It was used for biochemical and tolerance tests.

Biochem/physiol Actions

脊髄における抑制性神経伝達物質であり、NMDAレセプターのアロステリック調節因子です。
Glycine has a pivotal role in lowering the plasma lipid levels in diabetic and obese patients by activating the CNS. During brain hypoxia glycine can stabilize the energetics disturbances in brain mitochondria. It also increases the in vitro development of porcine blastocysts when used along with glucose.

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保管分類

11 - Combustible Solids

ppe

Eyeshields, Gloves, type N95 (US)

flash_point_f

No data available

flash_point_c

No data available

最新バージョンのいずれかを選択してください：

試験成績書（COA）

Lot/Batch Number
SDBB7510
SDBB5718
SDBB2412
SDBB2363
STBL3195

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A A Selin et al.
Bulletin of experimental biology and medicine, 153(1), 44-47 (2012-07-19)
Glycine stabilizes energetics of brain mitochondria under conditions of brain hypoxia in vivo modeled by ligation of the common carotid artery in rats. Hypoxia reduced respiratory control in brain cortex mitochondria from 7.7 ± 0.5 to 4.5 ± 0.3. Preliminary
F Megraud et al.
Journal of clinical microbiology, 22(6), 1007-1010 (1985-12-01)
"Campylobacter pyloridis" has been recently described as a gastritis-associated bacterium. We studied 20 strains. The bacteria had most of the characteristics of Campylobacter spp. strains. They were hippurate negative and tolerant to triphenyl tetrazolium chloride (at 0.4 and 1 mg/ml).
Jessica T Y Yue et al.
Circulation research, 110(10), 1345-1354 (2012-04-05)
Dysregulation of hepatic triglyceride (TG)-rich very low-density lipoproteins (VLDL-TG) in obesity and type 2 diabetes contributes to the dyslipidemia that leads to cardiovascular morbidity. The central nervous system (CNS), particularly the hypothalamus, regulates hepatic lipid metabolism. Although the underlying neurocircuitry
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