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Merck

D8802

デキストラン 溶液 from Leuconostoc mesenteroides

20 % (w/w) (Autoclaved)

別名:

repeating α-linked D-glucopyranosyl units, synthesized from sucrose by Leuconostoc mesenteroides

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この商品について

CAS番号:
UNSPSC Code:
12352201
NACRES:
NA.75
MDL number:
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form

liquid

Quality Level

mol wt

average mol wt ~500,000

concentration

20 % (w/w) (Autoclaved)

technique(s)

titration: suitable

color

colorless

density

1.00-1.20 g/mL

application(s)

hematology
histology

storage temp.

2-8°C

SMILES string

O1C(C(C(C(C1CO)O)O)O)OCC2OC(C(C(C2O)O)O)OCC(O)C(O)C(O)C(O)C=O

InChI

1S/C18H32O16/c19-1-5(21)9(23)10(24)6(22)3-31-17-16(30)14(28)12(26)8(34-17)4-32-18-15(29)13(27)11(25)7(2-20)33-18/h1,5-18,20-30H,2-4H2

InChI key

FZWBNHMXJMCXLU-UHFFFAOYSA-N

General description

Dextrans are polysaccharides with molecular weights ≥1,000 Dalton, with a linear backbone of α-linked D-glucopyranosyl repeating units. Dextrans are found as bacterial extracellular polysaccharides. They are synthesized from sucrose by Leuconostoc mesenteroides. Bacteria employ dextran in biofilm formation or as a protective coating to evade host phagocytes in the case of pathogenic bacteria.

Application

Use of dextrans as long and hydrophilic spacer arms to improve the performance of immobilized proteins acting on macromolecules.
Dextrans are used in many applications as platelet aggregants, plasma volume extenders, osmotic pressure regulators, stabilizers, organ separation media, matrix components, copolymers, microcarriers, binding agents, viscosity modifiers, antithrombotics, lubricants, and physical structure components.Dextran from Leuconostoc mesenteroides (Mw: 670,000) may be used as an analytical standard to calibrate the column for gel permeation chromatography (GPC). It has been used to sediment erythrocytes from blood along with 0.9% sodium chloride.



保管分類

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable



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Formyl Met-Leu-Phe-Stimulated FPR1 Phosphorylation in Plate-Adherent Human Neutrophils: Enhanced Proteolysis but Lack of Inhibition by Platelet-Activating Factor
Algirdas J, et al.
Journal of immunology research (2018)
Ana Luisa Miranda-Vilela et al.
Journal of biomedical nanotechnology, 9(7), 1261-1271 (2013-08-06)
This work aimed to test a dextran-functionalized magnetic fluid (DexMF) sample in mediating magnetohyperthermia to treat an advanced clinical Ehrlich-solid-tumor, to verify the effects of oral antioxidant administration of pequi-oil on this treatment and to investigate the potential of these
Ngalle Eric Mbua et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(25), 10207-10212 (2013-06-05)
Niemann-Pick type C (NPC) disease is characterized by impaired cholesterol efflux from late endosomes and lysosomes and secondary accumulation of lipids. Although impaired trafficking of individual glycoproteins and glycolipids has been noted in NPC cells and other storage disorders, there