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Merck

209198

Copper(II) sulfate pentahydrate

ACS reagent, ≥98.0%

Synonym(s):

Cupric sulfate pentahydrate, Sulfuric acid, copper(II) salt (1:1) pentahydrate

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About This Item

Linear Formula:
CuSO4 · 5H2O
CAS Number:
Molecular Weight:
249.69
NACRES:
NA.21
PubChem Substance ID:
UNSPSC Code:
12352302
EC Number:
231-847-6
MDL number:
Assay:
≥98.0%, 98.0-102.0% (ACS specification)
Grade:
ACS reagent
Form:
crystals
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grade

ACS reagent

Quality Segment

vapor pressure

7.3 mmHg ( 25 °C)

assay

≥98.0%, 98.0-102.0% (ACS specification)

form

crystals

reaction suitability

reaction type: click chemistry, reagent type: catalyst
core: copper

pH

3.5-4.5 (20 °C, 50 g/L)

mp

110 °C (dec.) (lit.)

anion traces

chloride (Cl-): ≤0.001%

cation traces

Ca: ≤0.005%, Fe: ≤0.003%, K: ≤0.01%, Na: ≤0.02%, Ni: ≤0.005%

SMILES string

O.O.O.O.O.[Cu++].[O-]S([O-])(=O)=O

InChI

1S/Cu.H2O4S.5H2O/c;1-5(2,3)4;;;;;/h;(H2,1,2,3,4);5*1H2/q+2;;;;;;/p-2

InChI key

JZCCFEFSEZPSOG-UHFFFAOYSA-L

General description

Copper(II) sulfate pentahydrate is a Lewis acid catalyst commonly used to promote acid-catalyzed organic transformations. It can also act as an effective redox catalyst in combination with other mixed oxidizing agents.

Application

Copper(II) sulfate pentahydrate can be used as a catalyst:      
  • In acetylation of alcohols and phenols in the presence of acetic anhydride.      
  • To synthesize various ynamides via intramolecular coupling of amides with alkynyl bromides.

It can also be used as a template in the synthesis of copper(II) ion-imprinted polymers using vinylpyridine and methacrylic acid as functional monomers. This polymer is used to quantify Cu2+ ion by using flame atomic absorption spectroscopy.

Features and Benefits

CuSO4.5H2O is an inexpensive, safe catalyst to be used in various organic transformations. It can also be recovered and reused in another reaction.


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Danger

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Storage Class

11 - Combustible Solids


Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

Deleterious substance

pdsc

Class I Designated Chemical Substances

prtr

Substances Subject to be Indicated Names

ishl_indicated

Substances Subject to be Notified Names

ishl_notified

209198-5G:4.548173115511E12 + 209198-100G:4.548173115474E12 + 209198-2.5KG:4.548173115481E12 + 209198-500G:4.548173115504E12 + 209198-250G:4.548173115498E12

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