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Merck

SML4028

ZH8667 Hydrochloride

≥98% (HPLC)

Synonym(s):

3′-Fluoro[1,1′-biphenyl]-4-ethanamine hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C14H14FN· HCl
CAS Number:
Molecular Weight:
251.73
UNSPSC Code:
12352116
NACRES:
NA.21
Assay:
≥98% (HPLC)
Form:
solid
Storage condition:
desiccated
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Quality Segment

assay

≥98% (HPLC)

form

solid

storage condition

desiccated

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

NCCC1=CC=C(C2=CC(F)=CC=C2)C=C1.Cl

InChI key

UFFLABDFGANWCU-UHFFFAOYSA-N

Biochem/physiol Actions

orally available, potent and selective activator of Trace amine-associated receptor 1 (TAAR1); only activates Gs in mTAAR1/hTAAR1-overexpressing cells.
ZH8667 is an orally available, potent and selective activator of Trace amine-associated receptor 1 (TAAR1). ZH8667 only activates Gs in mTAAR1/hTAAR1-overexpressing cells (EC50 = 1.17 nM (Gs).


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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