G5889

L-Glutamic acid monosodium salt hydrate

Name: <SC>L</SC>-Glutamic acid monosodium salt hydrate
Brand: SIGMA

BioReagent, suitable for cell culture, suitable for insect cell culture, ≥99%

Synonym(s):

(S)-2-Aminopentanedioic acid, L-Glutamic acid monosodium salt, Glu, MSG, Monosodium glutamate

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All Photos(4)

About This Item

Empirical Formula (Hill Notation):

C₅H₈NNaO₄ · xH₂O

CAS Number:

142-47-2

Molecular Weight:

169.11 (anhydrous basis)

MDL number:

MFCD00013074

UNSPSC Code:

12352209

PubChem Substance ID:

24895237

EC Number:

205-538-1

NACRES:

NA.75

Product Name

L-Glutamic acid monosodium salt hydrate, BioReagent, suitable for cell culture, suitable for insect cell culture, ≥99%

SMILES string

[NaH].NC(CCC(=O)O)C(=O)O.O

InChI key

JYDGDQPVBSBYRT-UHFFFAOYSA-N

InChI

1S/C5H9NO4.Na.H2O.H/c6-3(5(9)10)1-2-4(7)8;;;/h3H,1-2,6H2,(H,7,8)(H,9,10);;1H2;

product line

BioReagent

assay

≥99%

form

powder

technique(s)

cell culture | insect: suitable
cell culture | mammalian: suitable

color

white to off-white

mp

163 °C

Quality Level

200

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Related Categories

Amino Acids

Biochemicals

Cell Culture Supplements & Reagents

Application

L-Glutamic acid monosodium salt hydrate has been used:

to prepare glutamate stock solution in HEPES-buffered saline (HBS) for glutamate perfusions
as a component in YNG (yeast nitrogen base glutamate) medium
used to treat HT22 hippocampal cells to study its effects on cell viability and to examine the expression of molecules related to apoptotic cell death
as a component of fresh media to culture neurons and to assess glutamate uptake

Biochem/physiol Actions

Agonist at kainate, NMDA, and quisqualate receptors; an excitatory amino acid neurotransmitter.

Monosodium glutamate (MSG) is a food additive and an environmental agent, that can affect inflammation.

General description

L-Glutamic acid/monosodium glutamate (MSG) is the sodium salt of glutamic acid. It is a commonly used food additive.

Storage Class

13 - Non Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number

0000485509

0000466819

0000444314

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Monosodium glutamate (MSG): a villain and promoter of liver inflammation and dysplasia

Nakanishi Y, et al.

Journal of Autoimmunity, 30(1-2), 42-50 (2008)

Neuroprotective actions of noradrenaline: effects on glutathione synthesis and activation of peroxisome proliferator activated receptor delta

Madrigal J LM, et al.

Journal of Neurochemistry, 103(5), 2092-2101 (2007)

Microfluidic local perfusion chambers for the visualization and manipulation of synapses

Taylor A M, et al.

Neuron, 66(1), 57-68 (2010)

Food and Toxicologic Pathology: An Overview

Haschek and Rousseaux's Handbook of Toxicologic Pathology, 1051-1076 (2013)

Neuroprotective effects of 2, 3, 5, 4?-tetrahydoxystilbene-2-O-beta-D-glucoside from Polygonum multiflorum against glutamate-induced oxidative toxicity in HT22 cells

Lee S Y, et al.

Journal of Ethnopharmacology, 195, 64-70 (2017)

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