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ABS448 Anti-CSN8 Antibody

Anti-CSN8 Antibody is a highly specific rabbit polyclonal antibody, that targets COP9 signalosome complex subunit 8 & has been tested in western blotting.

Anti-CSN8 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Signaling Research Sub-Category: Developmental Signaling Gene Symbol: COPS8, CSN8 UniProt Number: Q99627
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ABS448
100 µg  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWBRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABS448
      ReplacesMABN1028
      DescriptionAnti-CSN8 Antibody
      Alternate Names
      • CSN8 Antibody
      • COP9 signalosome complex subunit 8
      • SGN8
      • JAB1-containing signalosome subunit 8
      • CSN8
      Background InformationCOP9 signalosome complex subunit 8 (CSN8, COPS8), also known as Signalosome subunit 8 (SGN8), is a nuclear-enriched protein complex belonging to the CSN8 family. It is comprised of eight subunits that interact with deubiquitinating enzymes and protein kinases. The CSN complex is involved in the regulation of various signaling and developmental processes, including DNA repair, cell cycle regulation, embryogenesis, axonal guidance, MAPK cascade, immune response, and hormonal signaling.
      References
      Product Information
      FormatAffinity Purified
      Control
      • Human liver tissue lysate
      PresentationPurified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-CSN8 Antibody is a highly specific rabbit polyclonal antibody, that targets COP9 signalosome complex subunit 8 & has been tested in western blotting.
      Key Applications
      • Western Blotting
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to the C-terminus of human CSN8.
      EpitopeC-terminus
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      SpecificityThis antibody recognizes the C-terminus of CSN8.
      Species Reactivity
      • Human
      Antibody TypePolyclonal Antibody
      Gene Symbol
      • COPS8
      • CSN8
      Purification MethodAntigen Affinity Purified
      UniProt Number
      Molecular Weight~27 and ~30 kDa observed. Uniprot describes 2 isoforms at ~18 kDa and ~23 kDa. Uncharacterized bands may appear in some lysate(s).
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in human liver tissue lysate.

      Western Blotting Analysis: 2 µg/mL of this antibody detected CSN8 in 15 µg of human liver tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      ABS448 04053252901256