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216100 Carboplatin - CAS 41575-94-4 - Calbiochem

An analog of Cisplatin with reduced nephrotoxicity. Displays potent antitumor activity.

Carboplatin - CAS 41575-94-4 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: cis-Diamine[1,1-cyclobutanedicarboxylato]platinum(II), JM-8, Paraplatin

Primary Target: Potent antitumor activity
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216100
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
41575-94-4C₆H₁₂N₂O₄Pt

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216100-25MGCN
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      		 Plastic ampoule 25 mg
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      Description
      OverviewAn analog of Cisplatin (Cat. No. 232120) with reduced nephrotoxicity. Displays potent antitumor activity.

      Note: Athough soluble in DMSO, Carboplatin is reported to be rendered inactive due to ligand displacement by the nucleophilic sulfur of DMSO. Water with or without 5% glucose is recommended for solubilization prior to culture treatment.
      Catalogue Number216100
      Brand Family Calbiochem®
      Synonymscis-Diamine[1,1-cyclobutanedicarboxylato]platinum(II), JM-8, Paraplatin
      References
      ReferencesHall, M.D., et al. 2014. Cancer Res. In press.
      Smith, I.E., et al. 1985. Cancer Treat. Rep. 69, 43.
      Harland, S.J., et al. 1984. Cancer Res. 44, 1693.
      Product Information
      CAS number41575-94-4
      ATP CompetitiveN
      FormWhite solid
      Hill FormulaC₆H₁₂N₂O₄Pt
      Chemical formulaC₆H₁₂N₂O₄Pt
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetPotent antitumor activity
      Purity≥98% by HPLC
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      RTECSTP2300000
      Safety Information
      R PhraseR: 20/21/22-42/43-46-61

      Harmful by inhalation, in contact with skin and if swallowed.
      May cause sensitization by inhalation and skin contact.
      May cause heritable genetic damage.
      May cause harm to the unborn child.
      S PhraseS: 22-26-36/37/39-45-53

      Do not breathe dust.
      In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
      Wear suitable protective clothing, gloves and eye/face protection.
      In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
      Avoid exposure - obtain special instructions before use.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Harmful & Carcinogenic / Teratogenic
      Storage +15°C to +30°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      216100-25MGCN 04055977219265

      Documentation

      Carboplatin - CAS 41575-94-4 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      Carboplatin - CAS 41575-94-4 - Calbiochem Certificates of Analysis

      TitleLot Number
      216100

      References

      Reference overview
      Hall, M.D., et al. 2014. Cancer Res. In press.
      Smith, I.E., et al. 1985. Cancer Treat. Rep. 69, 43.
      Harland, S.J., et al. 1984. Cancer Res. 44, 1693.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision08-July-2014 JSW
      Synonymscis-Diamine[1,1-cyclobutanedicarboxylato]platinum(II), JM-8, Paraplatin
      DescriptionAn analog of cisplatin with reduced nephrotoxicity. Displays potent antitumor activity.

      Note: Athough soluble in DMSO, Carboplatin is reported to be rendered inactive due to ligand displacement by the nucleophilic sulfur of DMSO. Water with or without 5% glucose is recommended for solubilization prior to culture treatment.
      FormWhite solid
      CAS number41575-94-4
      RTECSTP2300000
      Chemical formulaC₆H₁₂N₂O₄Pt
      Structure formulaStructure formula
      Purity≥98% by HPLC
      SolubilityH₂O with 5% Glucose (10 mg/mL)
      Storage +15°C to +30°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Harmful & Carcinogenic / Teratogenic
      Merck USA index14, 1822
      ReferencesHall, M.D., et al. 2014. Cancer Res. In press.
      Smith, I.E., et al. 1985. Cancer Treat. Rep. 69, 43.
      Harland, S.J., et al. 1984. Cancer Res. 44, 1693.