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101587 L-Arginine

Overview

Replacement Information

Key Spec Table

CAS #EC NumberHill FormulaMolar MassGrade Value
74-79-3200-811-1C₆H₁₄N₄O₂174.2 g/molPh Eur,ChP,JP,USP

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1.01587.9010.BWT
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      Plastic drum 10 kg
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      Description
      Catalogue Number101587
      SynonymsArg
      References
      Product Information
      CAS number74-79-3
      EC number200-811-1
      GradePh Eur,ChP,JP,USP
      Hill FormulaC₆H₁₄N₄O₂
      Molar Mass174.2 g/mol
      HS Code2925 29 00
      Structure formula ImageStructure formula Image
      Quality LevelMQ500
      Applications
      Biological Information
      Physicochemical Information
      Density1.1 g/cm3
      Melting Point223 - 224 °C (decomposition)
      pH value11.4 (100 g/l, H₂O, 20 °C)
      Vapor pressure<0.1 hPa (25 °C)
      Bulk density640 kg/m3
      Solubility148.7 g/l
      Dimensions
      Materials Information
      Toxicological Information
      LD 50 oralLD50 Rat > 5110 mg/kg
      Safety Information according to GHS
      RTECSCF1934200
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Assay (perchloric acid titration, calculated on dried substance)99.0 - 101.0 %
      Identity (IR-spectrum)passes test
      Identity (TLC)passes test
      Identity (specific rotation)passes test
      Appearancewhite to almost white, crystalline powder or colorless crystals
      Appearance of solution (50 g/l; water)clear and not more intense in color than reference solution BY₆
      Appearance of solution (100 g/l, CO₂-free water)clear and colorless
      Transmittance of solution (100 g/l, water)≥ 98.0 %
      Spec. rotation (α 20/D, 80 g/l, hydrochloric acid 250 g/l, calc. on dried substance)+25.5 to +28.5
      Spec. rotation (α 20/D, 80 g/l, hydrochloric acid 6 mol/l, calc. on dried substance)+26.9 to +27.9
      Spec. rotation (α 25/D, 80 g/l, hydrochloric acid 6 mol/l, calc. on dried substance)+26.3 to +27.7
      Spec. rotation (α 20/D, 80 g/l, hydrochloric acid 6 mol/l,previously dried substance)+26.9 to +27.9
      pH (100 g/l, CO₂-free water)10.5 - 12.0
      Alkalinity (100 g/l, water)10.5 - 12.0
      Proteinspasses test
      Chloride (Cl)≤ 200 ppm
      Sulfate (SO₄)≤ 200 ppm
      Heavy metals (as Pb)≤ 10 ppm
      As (Arsenic)≤ 1 ppm
      Cu (Copper)*≤ 25 ppm
      Fe (Iron)≤ 10 ppm
      Mn (Manganese)≤ 25 ppm
      Mo (Molybdenum)*≤ 2.5 ppm
      Ni (Nickel)≤ 2 ppm
      Zn (Zinc)≤ 130 ppm
      Other amino acids (TLC)≤ 0.4 %
      Related substances (TLC)passes test
      Related Compounds, total (TLC)≤ 0.5 %
      Ninhydrin-positive substances (LC) (any ninhydrin-positive impurity)≤ 0.2 %
      Ninhydrin-positive substances (LC) (ammonium (570 nm))≤ 0.02 %
      Ninhydrin-positive substances (LC) (total impurities)≤ 0.5 %
      Residual solvents (ICH Q3C)excluded by manufacturing process
      Sulfated ash (600 °C)≤ 0.1 %
      Loss on drying (105 °C; 3 h)≤ 0.30 %
      Bacterial endotoxins≤ 2.0 I.U./g
      Bacterial endotoxins (ChP)< 10.0
      Microbiological test (total aerobic microbial count (TAMC))≤ 10²
      Microbiological test (total yeast and mould count (TYMC))≤ 10¹
      Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
      Corresponds to Ph. Eur., ChP, JP, USP.
      Global Trade Item Number
      Catalogue Number GTIN
      1.01587.9010.BWT 0

      Documentation

      Material Qualification Dossier

      TitleVersion
      10.0

      Quality Management Dossier (Open Access)

      Title

      Operational Excellence Dossier

      Title

      L-Arginine SDS

      Title

      Safety Data Sheet (SDS) 

      L-Arginine Certificates of Analysis

      Product Number PackagingSpecificationLot Number
      1.01587.9010.BWT Plastic drumPDF Specification Document

      Certificates

      Title