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Merck

GF327

IL-15,
Human Recombinant Animal Free

Synonym(s):

Interleukin-15, IL15

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About This Item

UNSPSC Code:
12352202
NACRES:
NA.77
eCl@ss:
32160405
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impurities

<0.1 μg/mg protein endotoxin (<1 EU/μg)

Quality Segment

UniProt accession no.

shipped in

dry ice

storage temp.

-10 to -25°C

General description

IL-15 is an immunomodulating cytokine that stimulates the proliferation of T lymphocytes and shares many biological properties with IL-2. IL-15 exerts its biological activities primarily on T cells. It is also essential in the development, survival and activation of NK cells. Increased expression of IL-15 has been implicated with rheumatoid arthritis, inflammatory bowl disease and diseases affiliated with retroviruses HIV and HTLV-I.
Recombinant human IL-15 is a 12.9 kDa protein consisting of 115 amino acid residues.

Physical form

Product is presented in 20 mM Sodium Phosphate, pH 8.0 and is filtered through a 0.2 micron filter before lyophilization.

Analysis Note

The ED50 was determined by its ability to stimulate the proliferation of mouse CTLL-2 cells. The expected ED50 is ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 10^6 units/mg.


Storage Class

11 - Combustible Solids

wgk

WGK 1



Certificates of Analysis (COA)

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