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Merck

HADCYMAG-61K

MILLIPLEX® Human Adipocyte Panel

Configurable Human Adipocyte 11-Plex Panel

Synonym(s):

adipocyte biomarker listing, adipokine assay snapshot, adipokine biomarker profile, adipokine detection kit, adipokine multiplex product sheet, adipose tissue biomarker details, human adipocyte assay overview, human adipocyte panel summary, human adipokine product info, human adipokine research tool

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About This Item

UNSPSC Code:
12161503
NACRES:
NA.84
eCl@ss:
32161000


Product Name

MILLIPLEX® Human Adipocyte Panel,

Quality Segment

description

Configurable Human Adipocyte 11-Plex Panel

species reactivity

human

packaging

pkg of 1 ea

manufacturer/tradename

Milliplex®

technique(s)

multiplexing: suitable

input

cell culture supernatant

assay range

accuracy: 100%
(IL-6), accuracy: 102%
(TNFα), accuracy: 103%
(MCP-1), accuracy: 83%
(PAI-1 (total)), accuracy: 99%
(HGF), sensitivity: 0.2 pg/mL
(MinDC+2SD; IL-8), sensitivity: 0.2 pg/mL
(MinDC+2SD; NGF), sensitivity: 0.2 pg/mL
(MinDC+2SD; TNF?), sensitivity: 0.6 pg/mL
(MinDC+2SD; IL-6), sensitivity: 10 pg/mL
(MinDC+2SD; Leptin), sensitivity: 15 pg/mL
(MinDC+2SD; Adiponectin), sensitivity: 2.0 pg/mL
(MinDC+2SD; IL-1?), sensitivity: 2.1 pg/mL
(MinDC+2SD; MCP-1), sensitivity: 3.0 pg/mL
(MinDC+2SD; HGF), sensitivity: 4.4 pg/mL
(MinDC+2SD; Resistin), sensitivity: 4.6 pg/mL
(MinDC+2SD; PAI-1 (total)), standard curve range: 0.29-4,000 pg/mL
(IL-8), standard curve range: 0.32-5,000 pg/mL
(NGF), standard curve range: 0.38-6,000 pg/mL
(TNFα), standard curve range: 0.51-8,000 pg/mL
(IL-1β), standard curve range: 0.96-150,000 pg/mL
(IL-6), standard curve range: 0.96-150,000 pg/mL
(MCP-1), standard curve range: 26-400,000 pg/mL
(Adipnectin), standard curve range: 6.4-100,000 pg/mL
(HGF), standard curve range: 6.4-100,000 pg/mL
(Resistin), standard curve range: 9.6-150,000 pg/mL
(Leptin), standard curve range: 9.6-150,000 pg/mL
(PAI-1), inter-assay cv: <15%
intra-assay cv: <10%
(Adiponectin), inter-assay cv: <15%
intra-assay cv: <10%
(IL-8), inter-assay cv: <15%
intra-assay cv: <10%
(MCP-1), inter-assay cv: <15%
intra-assay cv: <10%
(Resistin), inter-assay cv: <20%
intra-assay cv: <10%
(HGF), inter-assay cv: <20%
intra-assay cv: <10%
(IL-6), inter-assay cv: <20%
intra-assay cv: <10%
(NGF), inter-assay cv: <20%
intra-assay cv: <10%
(PAI-1 (total)), inter-assay cv: <20%
intra-assay cv: <10%
(TNFα), inter-assay cv: <20%
intra-assay cv: <15%
(IL-1β), inter-assay cv: <25%
intra-assay cv: <20%
(Leptin)

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

General description

Adipose tissue plays a central role in metabolic regulation and inflammation. This set of biomarkers includes Adiponectin, HGF, IL-1β, IL-6, IL-8/CXCL8, Leptin, MCP-1/CCL2, NGF, PAI-1 (total), Resistin, and TNFα, which are key mediators of adipocyte function and immune signaling. These analytes provide insights into processes such as insulin sensitivity, lipid metabolism, inflammatory response, and adipose tissue remodeling. Their measurement supports research into obesity, metabolic syndrome, type 2 diabetes, and related inflammatory conditions.

Application

MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 11 analytes in human cell or tissue culture supernatants.

Analytes included: Adiponectin, HGF, IL-1β, IL-6, IL-8/CXCL8, Leptin, MCP-1/CCL2, NGF, PAI-1 (total), Resistin, TNFα

Assay Characteristics: Refer to assay protocol for details on cross-reactivity, sensitivity, precision, and accuracy.

Features and Benefits

Features: Targets key adipokines and cytokines involved in metabolic and inflammatory processes Includes 11 analytes relevant to adipocyte function, inflammation, and energy homeostasis Multiplex format enables simultaneous detection from minimal sample volume Compatible with human cell culture supernatants and tissue extracts Designed for research in obesity, insulin resistance, and metabolic syndrome
Benefits: Provides a comprehensive profile of adipocyte-derived signaling molecules Supports investigation of inflammation and metabolic dysregulation in human models Facilitates evaluation of therapeutic interventions targeting adipose tissue function Enables high-throughput analysis with reduced sample and reagent use Delivers reproducible, sensitive results for translational and preclinical research

Legal Information

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Disclaimer

For research use only. Not for use in diagnostic procedures.

Label License/Sticker for Assay Product:

By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.


pictograms

Skull and crossbonesEnvironment

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Skin Sens. 1

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3



Certificates of Analysis (COA)

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