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Merck

373272

HECAMEG

Non-ionic detergent useful for solubilization of membrane-bound proteins in their native state. Easily removed by dialysis.

Synonym(s):

Methyl-6-O-(N-heptylcarbamoyl)-α-D-glucopyranoside

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About This Item

Empirical Formula (Hill Notation):
C15H29NO7
CAS Number:
Molecular Weight:
335.39
UNSPSC Code:
12161902
NACRES:
NA.21
MDL number:
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Product Name

HECAMEG, Non-ionic detergent useful for solubilization of membrane-bound proteins in their native state. Easily removed by dialysis.

SMILES string

N(CCCCCCC)C(=O)OC[C@H]1O[C@@H]([C@@H]([C@H]([C@@H]1O)O)O)OC

InChI

1S/C15H29NO7/c1-3-4-5-6-7-8-16-15(20)22-9-10-11(17)12(18)13(19)14(21-2)23-10/h10-14,17-19H,3-9H2,1-2H3,(H,16,20)/t10-,11-,12+,13-,14+/m1/s1

InChI key

XPIVOYOQXKNYHA-RGDJUOJXSA-N

assay

≥95% (HPLC)

form

crystalline solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

color

white

CMC

19.5 mM

solubility

water: 10 mg/mL

shipped in

ambient

storage temp.

15-25°C

Quality Level

Application


  • An assessment of the biochemical applications of the non-ionic surfactant Hecameg.: This foundational study explores the biochemical applications of Hecameg, particularly its efficacy in solubilizing membrane proteins without denaturation, making it a valuable tool in membrane biochemistry research (Ruiz et al., 1994).

  • Purification and characterization of the cytochrome b6 f complex from Chlamydomonas reinhardtii.: Hecameg is utilized in this study for the purification of the cytochrome b6 f complex, demonstrating its effectiveness in maintaining the functional integrity of membrane protein complexes during isolation (Pierre et al., 1995).

  • Development of an improved in vitro activity assay for medium chain length PHA polymerases based on CoenzymeA release measurements.: This article describes the use of Hecameg in an improved assay for polymerase activity, emphasizing its role in biochemical methods that require the stabilization of enzyme activities (de Roo et al., 2000).

Disclaimer

Toxicity: Standard Handling (A)

General description

Non-ionic detergent useful for solubilization of membrane-bound proteins in their native state. Easily removed by dialysis.
Nonionic detergent useful for solubilization of membrane-bound proteins in their native state. Easily removed by dialysis. Has a CMC of 19.5 mM.

Other Notes

Plusquellec, D., et al. 1989. Anal. Biochem.179, 145.

Preparation Note

Following reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 3 months at 4°C.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

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Global Trade Item Number

SKUGTIN
373272-5GMCN04055977191035

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