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Merck

GF167

BMP-4 Protein, Human Recombinant

The Bone morphogenetic protein 4 (or BMP-4 protein) is a TGFβ superfamily ligand that is widely expressed from early embryogenesis through adulthood.

Synonym(s):

BMP4, Bone morphogentic protein-4, DVR-4

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About This Item

UNSPSC Code:
12352202
NACRES:
NA.77
eCl@ss:
32160405

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Product Name

BMP-4 Protein, Human Recombinant, The Bone morphogenetic protein 4 (or BMP-4 protein) is a TGFβ superfamily ligand that is widely expressed from early embryogenesis through adulthood.

assay

>97% (SDS-PAGE and HPLC)

impurities

<0.1 μg/mg protein endotoxin (<1EU/μg)

NCBI accession no.

NM_001202.3
NM_130850.2
NM_130851.2

UniProt accession no.

P12644

shipped in

dry ice

Quality Level

100

Related Categories

Analysis Note

Bioactivity assay: Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells.

Application

Research Category
Stem Cell Research
Research Sub Category
Growth Factors & Receptors

Biochem/physiol Actions

Cross Reactivty
None

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Bone morphogentic protein 4 (BMP-4) is a TGFβ superfamily ligand that is widely expressed from early embryogenesis through adulthood. It plays an important role in mesenchyme formation, epidermal determination, suppression of neural induction, the development of multiple organs, and tissue repair. Like BMP-7, BMP-4 is involved in the development and maintenance of bone and cartilage. Reduced expression of BMP-4 is associated with a number of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Recombinant human BMP-4, expressed in HeLa cells, is a 31-36 kDa homodimeric glycoprotein.
Product Source: Hela Cells

Physical form

Product is filtered through a 0.2 micron filter before lyophilization.

Preparation Note

Store at -20°C for up to 6 months from date of receipt.

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Global Trade Item Number

SKUGTIN
GF16704053252691249

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