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101500 AEBSF, Hydrochloride - CAS 30827-99-7 - Calbiochem

101500
가격 및 재고 조회

개요

Replacement Information

주요 사양표

CAS #Empirical Formula
30827-99-7C₈H₁₀FNO₂S · HCl

가격 및 재고여부

카탈로그 번호 재고 정보패킹 포장 단위 가격(VAT 별도) 수량
101500-100MGCN
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      Glass bottle 100 mg
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      가격 문의 추가 정보
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      101500-1GMCN
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          Glass bottle 1 gm
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          가격 문의
          101500-500MGCN
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              Plastic ampoule 500 mg
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              가격 문의
              101500-50MGCN
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                  Remaining: will advise
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                  Glass bottle 50 mg
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                  가격을 검색할 수 없습니다
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                  Maximum Quantity is
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                  가격 문의
                  Description
                  OverviewSpecific, irreversible inhibitor of serine proteases. Inhibits chymotrypsin, kallikrein, plasmin, thrombin, trypsin, and related thrombolytic enzymes. Stable, nontoxic alternative to PMSF (Cat. No. 52332) and DFP (Cat. No. 30967). A β-secretase inhibitor that inhibits β-amyloid peptide (Aβ) production and enhances amyloid precursor protein (sAPPUα) secretion in several cell lines at millimolar concentrations. Use at the same molar concentrations (0.1-1.0 mM) as PMSF for most applications. Also available as a 50 mM solution in H2O (Cat. No. 508436).
                  Catalogue Number101500
                  Brand Family Calbiochem®
                  Synonyms4-(2-Aminoethyl)benzenesulfonylfluoride, HCl
                  Application Data
                  References
                  ReferencesCitron, M., et al. 1996. Neuron 17, 171.
                  Ohkubo, I., et al. 1994. J. Biochem. 116, 1182.
                  Mintz, G.R. 1993. BioPharm. 6, 34.
                  Lawson, W.B., et al. 1982. Folia Haematol. 109, 52.
                  Markwardt, F., et al. 1974. Biochem. Pharmacol. 23, 2247.
                  Markwardt, F., et al. 1973. Thromb. Res. 2, 343.
                  Baker, B.R., and Cory, M. 1971. J. Med. Chem. 14, 119.
                  Product Information
                  CAS number30827-99-7
                  ATP CompetitiveN
                  FormWhite to off-white solid
                  Hill FormulaC₈H₁₀FNO₂S · HCl
                  Chemical formulaC₈H₁₀FNO₂S · HCl
                  ReversibleN
                  Structure formula ImageStructure formula Image
                  Quality LevelMQ100
                  Applications
                  Biological Information
                  Primary Targetchymotrypsin
                  Purity>97% by HPLC
                  Physicochemical Information
                  Cell permeableN
                  Dimensions
                  Materials Information
                  Toxicological Information
                  Safety Information according to GHS
                  Safety Information
                  Product Usage Statements
                  Storage and Shipping Information
                  Ship Code Ambient Temperature Only
                  Toxicity Standard Handling
                  Storage -20°C
                  Protect from Moisture Protect from moisture
                  Do not freeze Ok to freeze
                  Special InstructionsFollowing reconstitution, store in the refrigerator (4°C). Aqueous stock solutions are stable for up to 2 months at 4°C. Slight hydrolysis occurs at alkaline pH (8-9).
                  Packaging Information
                  Packaged under inert gas Packaged under inert gas
                  Transport Information
                  Supplemental Information
                  Specifications

                  Documentation

                  AEBSF, Hydrochloride - CAS 30827-99-7 - Calbiochem MSDS

                  타이틀

                  물질안전보건자료(MSDS) 

                  AEBSF, Hydrochloride - CAS 30827-99-7 - Calbiochem Certificates of Analysis

                  TitleLot Number
                  101500

                  References

                  참고문헌 보기
                  Citron, M., et al. 1996. Neuron 17, 171.
                  Ohkubo, I., et al. 1994. J. Biochem. 116, 1182.
                  Mintz, G.R. 1993. BioPharm. 6, 34.
                  Lawson, W.B., et al. 1982. Folia Haematol. 109, 52.
                  Markwardt, F., et al. 1974. Biochem. Pharmacol. 23, 2247.
                  Markwardt, F., et al. 1973. Thromb. Res. 2, 343.
                  Baker, B.R., and Cory, M. 1971. J. Med. Chem. 14, 119.

                  Brochure

                  Title
                  Bulk Product Guide

                  Citations

                  타이틀
                • Catherine Mee-Hie Cho, Ashok Mulchandani and Wilfred Chen. (2006) Functional analysis of organophosphorus hydrolase variants with high degradation activity towards organophosphate pesticides. Protein Engineering Design and Selection 19, 99-105.
                • Ok Hee Ryu, et al. (2005) Proteolysis of MIP-1α isoforms LD78β and LD78α by neutrophil-derived serine proteases. Journal of Biological Chemistry 280, 17415-17421.
                • Sharon Yagur-Kroll and Orna Amster-Choder. (2005) Dynamic membrane topology of the E. coli -glucoside transporter β-glucosidase transporter BglF. Journal of Biological Chemistry 280, 19306-19318.
                • Valerie A. Fadok, et al. (2001) Differential Effects of Apoptotic Versus Lysed Cells on Macrophage Production of Cytokines: Role of Proteases. Journal of Immunology 166, 6847-6854.
                • Data Sheet

                  Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

                  Revision27-September-2013 JSW
                  Synonyms4-(2-Aminoethyl)benzenesulfonylfluoride, HCl
                  Application Data
                  DescriptionSpecific irreversible inhibitor of serine proteases. Reacts covalently with a serine at the active site. Inhibits chymotrypsin, kallikrein, plasmin, thrombin, trypsin, and related thrombolytic enzymes. Stable, nontoxic alternative to PMSF (Cat. No. 52332) and DFP (Cat. No. 30967). Used at the same molar concentration (0.1-1.0 mM) as PMSF for most applications. Exhibits low inhibitory activity towards proteinase K.
                  FormWhite to off-white solid
                  Intert gas (Yes/No) Packaged under inert gas
                  CAS number30827-99-7
                  Chemical formulaC₈H₁₀FNO₂S · HCl
                  Structure formulaStructure formula
                  Purity>97% by HPLC
                  SolubilityH₂O (25 mg/ml)
                  Storage -20°C
                  Protect from moisture
                  Do Not Freeze Ok to freeze
                  Special InstructionsFollowing reconstitution, store in the refrigerator (4°C). Aqueous stock solutions are stable for up to 2 months at 4°C. Slight hydrolysis occurs at alkaline pH (8-9).
                  Toxicity Standard Handling
                  ReferencesCitron, M., et al. 1996. Neuron 17, 171.
                  Ohkubo, I., et al. 1994. J. Biochem. 116, 1182.
                  Mintz, G.R. 1993. BioPharm. 6, 34.
                  Lawson, W.B., et al. 1982. Folia Haematol. 109, 52.
                  Markwardt, F., et al. 1974. Biochem. Pharmacol. 23, 2247.
                  Markwardt, F., et al. 1973. Thromb. Res. 2, 343.
                  Baker, B.R., and Cory, M. 1971. J. Med. Chem. 14, 119.
                  Citation
                • Catherine Mee-Hie Cho, Ashok Mulchandani and Wilfred Chen. (2006) Functional analysis of organophosphorus hydrolase variants with high degradation activity towards organophosphate pesticides. Protein Engineering Design and Selection 19, 99-105.
                • Ok Hee Ryu, et al. (2005) Proteolysis of MIP-1α isoforms LD78β and LD78α by neutrophil-derived serine proteases. Journal of Biological Chemistry 280, 17415-17421.
                • Sharon Yagur-Kroll and Orna Amster-Choder. (2005) Dynamic membrane topology of the E. coli -glucoside transporter β-glucosidase transporter BglF. Journal of Biological Chemistry 280, 19306-19318.
                • Valerie A. Fadok, et al. (2001) Differential Effects of Apoptotic Versus Lysed Cells on Macrophage Production of Cytokines: Role of Proteases. Journal of Immunology 166, 6847-6854.
                • 관련 제품 및 어플리케이션

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                  카테고리

                  Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Proteases Inhibitors