Millipore Sigma Vibrant Logo

124009 Akt Inhibitor III - Calbiochem

124009
가격 및 재고 조회

개요

Replacement Information

주요 사양표

Empirical Formula
C₂₈H₅₇O₉P

가격 및 재고여부

카탈로그 번호 재고 정보패킹 포장 단위 가격(VAT 별도) 수량
124009-1MGCN
재고 정보 검색...
재고 없음재고 없음
예상 출고 가능일 
단종품
제한된 수량 가능
재고여부 확인
    Remaining: will advise
      Remaining: will advise
      추천사항
      고객 서비스로 문의
      Contact Customer Service

      Plastic ampoule 1 mg
      가격 검색...
      가격을 검색할 수 없습니다
      Minimum Quantity needs to be mulitiple of
      Maximum Quantity is
      가격 문의 추가 정보
      ()이 할인됨
       
      가격 문의
      Description
      OverviewA cell permeable, reversible, and substrate competitive phosphatidylinositol analog that inhibits the activation of Akt and select downstream substrates without decreasing phosphorylation of PDK-1 or other kinases downstream of Ras, such as MAPK. Also acts as a potent inducer of apoptosis and selectively kills a variety of cancer cell lines that contain high levels of active Akt. When used at a concentration of 10 µM, it is reported to activate p38α/SAPK2α MAP kinase. At 10 µM it will also inhibit PKA activity.
      Catalogue Number124009
      Brand Family Calbiochem®
      SynonymsSH-6
      References
      ReferencesGills, J.J., et al. 2007. J. Biol. Chem. in press.
      Kozikowski, A.P., et al. 2003. J. Am. Chem. Soc.125, 1144.
      Product Information
      ATP CompetitiveN
      FormWhite solid
      Hill FormulaC₂₈H₅₇O₉P
      Chemical formulaC₂₈H₅₇O₉P
      ReversibleY
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetAkt
      Purity≥98% by NMR
      Physicochemical Information
      Cell permeableY
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Akt Inhibitor III - Calbiochem MSDS

      타이틀

      물질안전보건자료(MSDS) 

      Akt Inhibitor III - Calbiochem Certificates of Analysis

      TitleLot Number
      124009

      References

      참고문헌 보기
      Gills, J.J., et al. 2007. J. Biol. Chem. in press.
      Kozikowski, A.P., et al. 2003. J. Am. Chem. Soc.125, 1144.

      Brochure

      Title
      Akt
      Biologics 31.1
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision03-October-2007 RFH
      SynonymsSH-6
      DescriptionA phosphatidylinositol analog that inhibits the activation of Akt and selected downstream substrates without affecting the phosphorylation of PDK-1 and other downstream kinases. Decreases phosphorylation of Akt without affecting the total Akt level. Reported to be a potent inducer of apoptosis and to selectively kill a variety of cancer cell lines expressing high levels of active Akt. When used at a concentration of 10 µM, it is reported to activate p38α/SAPK2α MAP kinase. At 10 µM it will also inhibit PKA activity.
      FormWhite solid
      Intert gas (Yes/No) Packaged under inert gas
      Chemical formulaC₂₈H₅₇O₉P
      Structure formulaStructure formula
      Purity≥98% by NMR
      SolubilityDMSO (10 mg/ml)
      Storage -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesGills, J.J., et al. 2007. J. Biol. Chem. in press.
      Kozikowski, A.P., et al. 2003. J. Am. Chem. Soc.125, 1144.