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Merck

AB15417

Anti-Beclin 1 Antibody

serum, Chemicon®

동의어(들):

Coiled-coil myosin-like BCL2-interacting protein, BECN1

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제품정보 (DICE 배송 시 비용 별도)

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ICC, IHC, WB
Citations:
2
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biological source

rabbit

Quality Segment

conjugate

unconjugated

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

immunocytochemistry: suitable, immunohistochemistry: suitable, western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... BECN1(8678)

General description

Autophagy is the process by which cells recycle cytoplasm and dispose of excess or defective organelles. This process is suggested to be involved development, differentiation, growth regulation and tissue remodeling in multicellular organisms. Beclin 1 is a BCL-2 interacting protein and this protein was shown to play a role in the promotion of autophagy.

Immunogen

Synthetic peptide corresponding to the C-terminus of human Beclin 1 protein.

Application

Detect Beclin 1 using this Anti-Beclin 1 Antibody validated for use in WB, IC, IH.
Research Category
Neuroscience
Research Sub Category
Neurodegenerative Diseases
Western blot: 1:100-1:2,000
Immunocytochemistry: 1:100-1:2,000
Immunohistochemistry: 1:100-1:2,000
Optimal working dilutions must be determined by end user.

Biochem/physiol Actions

Beclin 1 [Coiled-coil myosin-like BCL2-interacting protein, BECN1].

Physical form

Lyophilized. Reconstitute with 50 μL of sterile distilled water. Centrifuge to remove any insoluble material. Contains no preservative.
Serum

Preparation Note

Maintain lyophilized material frozen at -20°C to -70°C for up to 12 months after date of receipt. After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles. Glycerol (1:1, ACS or better grade) can be added for additional stability.

Other Notes

Replaces: MABN16

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


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10 - Combustible liquids



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