Anti-Proline-rich Protein 14 Antibody

Proline-rich protein 14 (UniProt Q9BWN1) is encoded by the PRR14 gene in human (Gene ID 78994). Proline-rich protein 14 participates in the tethering of heterochromatin to the inner nuclear periphery by associating with the nuclear lamina and attaching to heterochromatin through its binding partner, heterochromatin protein 1 (HP1). After disassembly early in mitosis, Proline-rich protein 14 reassembles via binding to anaphase chromosomes through HP1, then via association with the nuclear lamina in telophase. PRR14 may thereby play a role in specifying HP1-bound heterochromatin for reattachment to the nuclear lamina at mitotic exit.

KLH-conjugated linear peptide corresponding to human Proline-rich Protein 14.

Anti-Proline-rich Protein 14 Antibody is an antibody against Proline-rich Protein 14 for use in Western Blotting.

Evaluated by Western Blotting in HeLa cell lysate.

Western Blotting Analysis: A 1:500 dilution of this antibody detected Proline-rich Protein 14 in 10 ug of HeLa cell lysate.

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