biological source
mouse
Quality Segment
conjugate
magnetic beads conjugate
antibody form
purified antibody
antibody product type
primary antibodies
clone
23A8, monoclonal
species reactivity
human, rat, mouse
technique(s)
immunoprecipitation (IP): suitable, western blot: suitable
isotype
IgG2b
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... RAC1(5879)
General description
Rac1 is a member of a RhoGTPase subfamily (Rac1-Rac4) that transduces extracellular signals from G-coupled protein receptors (GPCR), integrins and growth factor receptors to effector molecules that modulate multiple signaling pathways. While Rac1 supports the activation of MAPkinase pathways and gene activation, it’s most important functions include the regulation of cytoskeletal structures. Together with Rho (regulator of stress fibers) and Cdc42 (regulator of filopodia), Rac modulates the formation of focal adhesion (FA) complexes; membrane ruffles and lamellipodia that contribute to important cell functions related to cell attachment and movement.
21 kDa
Application
Anti-Rac1 Antibody, clone 23A8, Magnetic bead Conjugate detects level of Rac1 & has been published & validated for use in WB & IP.
Biochem/physiol Actions
Other species have not been tested.
Recognizes human Rac1.
Preparation Note
Stable for 1 year at 2-8°C from date of receipt. DO NOT FREEZE! Wash the magnetic beads with an appropriate buffer prior to use to remove sodium azide.
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저장 등급
10 - Combustible liquids
wgk
WGK 2
시험 성적서(COA)
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국제 무역 품목 번호
| SKU | GTIN |
|---|---|
| 16-319 | 04053252292361 |