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203303 Bisindolylmaleimide V - CAS 113963-68-1 - Calbiochem

203303
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개요

Replacement Information

주요 사양표

CAS #Empirical Formula
113963-68-1C₂₁H₁₅N₃O₂

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카탈로그 번호 재고 정보패킹 포장 단위 가격(VAT 별도) 수량
203303-1MGCN
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      Plastic ampoule 1 mg
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      203303-250UGCN
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          Plastic ampoule 250 μg
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          Description
          OverviewA cell-permeable negative control compound for protein kinase C inhibition studies (IC50 >100 µM). Blocks the activation of mitogen-stimulated protein kinase p70s6k/p85s6k in vivo (IC50 8 µM).
          Catalogue Number203303
          Brand Family Calbiochem®
          Synonyms2,3-bis(1H-Indol-3-yl)-N-methylmaleimide, Ro 31-6045
          References
          ReferencesMarmy-Conus, N., et al. 2002. FEBS Lett. 26094 (In Press) 1-6.
          Davis, P.D., et al. 1992. J. Med. Chem. 35, 177.
          Toullec, D., et al. 1991. J. Biol. Chem. 266, 15771.
          Product Information
          CAS number113963-68-1
          ATP CompetitiveN
          FormRedish orange solid
          Hill FormulaC₂₁H₁₅N₃O₂
          Chemical formulaC₂₁H₁₅N₃O₂
          ReversibleN
          Structure formula ImageStructure formula Image
          Quality LevelMQ100
          Applications
          Biological Information
          Primary TargetNegative control compound for protein kinase C inhibition
          Primary Target IC<sub>50</sub>>100 µM as negative control compound for protein kinase C inhibition; 8 µM in blocking the activation of mitogen-stimulated protein kinase p70s6k/p85s6k in vivo
          Purity≥95% by HPLC
          Physicochemical Information
          Cell permeableY
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage +2°C to +8°C
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          Bisindolylmaleimide V - CAS 113963-68-1 - Calbiochem MSDS

          타이틀

          물질안전보건자료(MSDS) 

          Bisindolylmaleimide V - CAS 113963-68-1 - Calbiochem Certificates of Analysis

          TitleLot Number
          203303

          References

          참고문헌 보기
          Marmy-Conus, N., et al. 2002. FEBS Lett. 26094 (In Press) 1-6.
          Davis, P.D., et al. 1992. J. Med. Chem. 35, 177.
          Toullec, D., et al. 1991. J. Biol. Chem. 266, 15771.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision20-May-2008 RFH
          Synonyms2,3-bis(1H-Indol-3-yl)-N-methylmaleimide, Ro 31-6045
          DescriptionA cell-permeable negative control compound for protein kinase C inhibition studies (IC50 > 100 µM). Blocks the activation of p70s6k/p85s6k in vivo (IC50 = 8 µM).
          FormRedish orange solid
          CAS number113963-68-1
          Chemical formulaC₂₁H₁₅N₃O₂
          Structure formulaStructure formula
          Purity≥95% by HPLC
          SolubilityDMSO (10 mg/ml) or Methanol (5 mg/ml)
          Storage +2°C to +8°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
          Toxicity Standard Handling
          ReferencesMarmy-Conus, N., et al. 2002. FEBS Lett. 26094 (In Press) 1-6.
          Davis, P.D., et al. 1992. J. Med. Chem. 35, 177.
          Toullec, D., et al. 1991. J. Biol. Chem. 266, 15771.