205530 CA-074 - Calbiochem

205530
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      가격 및 재고 조회

      개요

      Replacement Information

      주요 사양표

      Empirical Formula
      C₁₈H₂₉N₃O₆

      가격 및 재고여부

      카탈로그 번호 재고 정보패킹 포장 단위 가격(VAT 별도) 수량
      205530-1MGCN
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          Plastic ampoule 1 mg
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          Description
          OverviewAn epoxysuccinyl peptide that acts as a potent, irreversible, and specific inhibitor of cathepsin B (IC50 = 2.24 nM for rat liver cathepsin B). Reduces ischemia-induced neuronal death. Exhibits lower membrane permeability when compared to CA-074 Me (Cat. No. 205531).
          Catalogue Number205530
          Brand Family Calbiochem®
          SynonymsCathepsin B Inhibitor III, [L-3-trans-(Propylcarbamoyl)oxirane-2-carbonyl]-L-isoleucyl-L-proline
          References
          ReferencesChan, V.J., et al. 1999. Biochem. J. 340, 113.
          Tsuchiya, K., et al. 1999. Exp. Neurol. 155, 187.
          Yamamoto, A., et al. 1997. J. Biochem. 121, 974.
          Inubushi, T., et al. 1994. J. Biochem. 116, 282.
          Murata, M., et al. 1991. FEBS Lett. 280, 307.
          Towatari, T., et al. 1991. FEBS Lett. 280, 311.
          Product Information
          ATP CompetitiveN
          FormColorless or white solid
          Hill FormulaC₁₈H₂₉N₃O₆
          Chemical formulaC₁₈H₂₉N₃O₆
          ReversibleN
          Structure formula ImageStructure formula Image
          Quality LevelMQ100
          Applications
          Biological Information
          Primary Targetcathepsin B
          Primary Target IC<sub>50</sub>2.24 nM for rat liver cathepsin B
          Purity≥98% by HPLC
          Physicochemical Information
          Cell permeableN
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage -20°C
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          CA-074 - Calbiochem MSDS

          타이틀

          물질안전보건자료(MSDS) 

          CA-074 - Calbiochem Certificates of Analysis

          TitleLot Number
          205530

          References

          참고문헌 보기
          Chan, V.J., et al. 1999. Biochem. J. 340, 113.
          Tsuchiya, K., et al. 1999. Exp. Neurol. 155, 187.
          Yamamoto, A., et al. 1997. J. Biochem. 121, 974.
          Inubushi, T., et al. 1994. J. Biochem. 116, 282.
          Murata, M., et al. 1991. FEBS Lett. 280, 307.
          Towatari, T., et al. 1991. FEBS Lett. 280, 311.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision27-May-2008 RFH
          SynonymsCathepsin B Inhibitor III, [L-3-trans-(Propylcarbamoyl)oxirane-2-carbonyl]-L-isoleucyl-L-proline
          DescriptionA potent, irreversible inhibitor of Cathepsin B in vivo and in vitro (IC50 = 2.24 nM for rat liver cathepsin B).
          FormColorless or white solid
          Chemical formulaC₁₈H₂₉N₃O₆
          Structure formulaStructure formula
          Purity≥98% by HPLC
          SolubilityDMSO (10 mg/ml)
          Storage -20°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Standard Handling
          ReferencesChan, V.J., et al. 1999. Biochem. J. 340, 113.
          Tsuchiya, K., et al. 1999. Exp. Neurol. 155, 187.
          Yamamoto, A., et al. 1997. J. Biochem. 121, 974.
          Inubushi, T., et al. 1994. J. Biochem. 116, 282.
          Murata, M., et al. 1991. FEBS Lett. 280, 307.
          Towatari, T., et al. 1991. FEBS Lett. 280, 311.