Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
From Catalog: Desc. Field- added "A 32 amino acid residue peptide that is shown to stimulate bone formation and inhibit bone resorption.
Calcitonin, Human Certificates of Analysis
Gennari, C. and Agnusdei, D. 1994. Br. J. Clin. Pract.48, 196. MacIntyre, I. et al. 1988. Clin. Orthop.217, 45. Chambers, T.J., et al. 1985. J. Pathol.145, 297.
Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
Calcitonin is a single-chain peptide hormone of 32 amino acid residues with a disulfide bridge between cysteines at positions 1 and 7. It is produced in the parafollicular C cells of the thyroid gland and acts to stimulate bone formation by osteoblasts and inhibits bone resorption. Part of the effect of calcitonin appears to be mediated through increasing cAMP concentrations in osteoclasts.