05-23-2402 Calcitonin, Human

05-23-2402
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      카탈로그 번호 재고 정보패킹 포장 단위 가격(VAT 별도) 수량
      05232402-0.5MGCN
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          Plastic ampoule .5 mg
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          Description
          OverviewSynthetic, human calcitonin. A 32 amino acid peptide that is shown to stimulate bone formation and inhibit bone resorption.
          Catalogue Number05-23-2402
          Brand Family Calbiochem®
          References
          ReferencesGennari, C. and Agnusdei, D. 1994. Br. J. Clin. Pract. 48, 196.
          MacIntyre, I. et al. 1988. Clin. Orthop. 217, 45.
          Chambers, T.J., et al. 1985. J. Pathol. 145, 297.
          Product Information
          CAS number21215-62-3
          FormLyophilized
          FormulationSold on the basis of peptide content.
          Hill FormulaC₁₅₁H₂₂₆N₄₀O₄₅S₃
          Chemical formulaC₁₅₁H₂₂₆N₄₀O₄₅S₃
          Hygroscopic Hygroscopic
          Sold on the basis of peptide contentY
          Quality LevelMQ100
          Applications
          Biological Information
          Purity≥96% by HPLC
          Physicochemical Information
          Peptide ContentY
          Peptide SequenceH-Cys¹-Gly-Asn-Leu-Ser-Thr-Cys⁷-Met-Leu-Gly-Thr-Tyr-Thr-Gln-Asp-Phe-Asn-Lys-Phe-His-Thr-Phe-Pro-Gln-Thr-Ala-Ile-Gly-Val-Gly-Ala-Pro-NH₂(disulfide bond: 1 → 7)
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          RTECSXP3560000
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage -20°C
          Hygroscopic Hygroscopic
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.



          From Catalog:
          Desc. Field- added "A 32 amino acid residue peptide that is shown to stimulate bone formation and inhibit bone resorption.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          Calcitonin, Human Certificates of Analysis

          TitleLot Number
          05-23-2402

          References

          참고문헌 보기
          Gennari, C. and Agnusdei, D. 1994. Br. J. Clin. Pract. 48, 196.
          MacIntyre, I. et al. 1988. Clin. Orthop. 217, 45.
          Chambers, T.J., et al. 1985. J. Pathol. 145, 297.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision18-September-2008 RFH
          DescriptionCalcitonin is a single-chain peptide hormone of 32 amino acid residues with a disulfide bridge between cysteines at positions 1 and 7. It is produced in the parafollicular C cells of the thyroid gland and acts to stimulate bone formation by osteoblasts and inhibits bone resorption. Part of the effect of calcitonin appears to be mediated through increasing cAMP concentrations in osteoclasts.
          FormLyophilized
          FormulationSold on the basis of peptide content.
          CAS number21215-62-3
          RTECSXP3560000
          Chemical formulaC₁₅₁H₂₂₆N₄₀O₄₅S₃
          Peptide SequenceH-Cys¹-Gly-Asn-Leu-Ser-Thr-Cys⁷-Met-Leu-Gly-Thr-Tyr-Thr-Gln-Asp-Phe-Asn-Lys-Phe-His-Thr-Phe-Pro-Gln-Thr-Ala-Ile-Gly-Val-Gly-Ala-Pro-NH₂(disulfide bond: 1 → 7)
          Purity≥96% by HPLC
          Solubility5% Acetic acid (1 mg/ml)
          Storage -20°C
          Hygroscopic
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.



          From Catalog:
          Desc. Field- added "A 32 amino acid residue peptide that is shown to stimulate bone formation and inhibit bone resorption.
          Toxicity Standard Handling
          Merck USA index14, 1643
          ReferencesGennari, C. and Agnusdei, D. 1994. Br. J. Clin. Pract. 48, 196.
          MacIntyre, I. et al. 1988. Clin. Orthop. 217, 45.
          Chambers, T.J., et al. 1985. J. Pathol. 145, 297.