208724 Calpain Inhibitor IV - Calbiochem

208724
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      가격 및 재고 조회

      개요

      Replacement Information

      주요 사양표

      Empirical Formula
      C₃₀H₄₀FN₃O₆

      가격 및 재고여부

      카탈로그 번호 재고 정보패킹 포장 단위 가격(VAT 별도) 수량
      208724-1MGCN
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          Plastic ampoule 1 mg
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          Description
          OverviewA potent, cell-permeable, and irreversible inhibitor of calpain II (k2 = 28,900 M-1s-1). Also acts as an inhibitor of cathepsin L (k2 = 680,000 M-1s-1).
          Catalogue Number208724
          Brand Family Calbiochem®
          SynonymsZ-LLY-FMK
          References
          ReferencesDutt, P., et al. 1998. FEBS Lett. 436, 367.
          Angliker, H., et al. 1992. J. Med. Chem. 35, 216.
          Product Information
          ATP CompetitiveN
          FormWhite to pale yellow solid
          Hill FormulaC₃₀H₄₀FN₃O₆
          Chemical formulaC₃₀H₄₀FN₃O₆
          ReversibleN
          Structure formula ImageStructure formula Image
          Quality LevelMQ100
          Applications
          ApplicationCalpain Inhibitor IV, Z-LLY-FMK, CAS 133410-84-1, is a cell-permeable, potent, irreversible inhibitor of calpain II (k2 = 28,900 M-1s-1). Also blocks cathepsin L activity (k2 = 680,000 M-1s-1).
          Biological Information
          Primary Targetcalpain 2
          Primary Target IC<sub>50</sub>k₂ = 28,900 M⁻¹s⁻¹ in the inhibition of calpain II; k2 = 680,000 M⁻¹s⁻¹ in the inhibition of cathepsin L
          Puritysingle spot by TLC
          Physicochemical Information
          Cell permeableY
          Peptide SequenceZ-Leu-Leu-Tyr-CH₂F
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage -20°C
          Protect from Moisture Protect from moisture
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          Calpain Inhibitor IV - Calbiochem MSDS

          타이틀

          물질안전보건자료(MSDS) 

          Calpain Inhibitor IV - Calbiochem Certificates of Analysis

          TitleLot Number
          208724

          References

          참고문헌 보기
          Dutt, P., et al. 1998. FEBS Lett. 436, 367.
          Angliker, H., et al. 1992. J. Med. Chem. 35, 216.

          Brochure

          Title
          Caspases and other Apoptosis Related Tools Brochure

          Citations

          타이틀
        • Georg Rosenberger, Andreas Gal and Kerstin Kutsche. (2005) αPIX associates with calpain 4, the small subunit of calpain, and has a dual role in integrin-mediated cell spreading. Journal of Biological Chemistry (280) 6879-6889.
        • Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision13-May-2013 JSW
          SynonymsZ-LLY-FMK
          DescriptionA potent, cell-permeable and irreversible inhibitor of calpain II (k2 = 28,900 M-1s-1). Also acts as an inhibitor of cathepsin L (k2 = 680,000 M-1s-1).
          FormWhite to pale yellow solid
          Chemical formulaC₃₀H₄₀FN₃O₆
          Peptide SequenceZ-Leu-Leu-Tyr-CH₂F
          Structure formulaStructure formula
          Puritysingle spot by TLC
          SolubilityDMSO (25 mg/ml)
          Storage -20°C
          Protect from moisture
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
          Toxicity Standard Handling
          ReferencesDutt, P., et al. 1998. FEBS Lett. 436, 367.
          Angliker, H., et al. 1992. J. Med. Chem. 35, 216.
          Citation
        • Georg Rosenberger, Andreas Gal and Kerstin Kutsche. (2005) αPIX associates with calpain 4, the small subunit of calpain, and has a dual role in integrin-mediated cell spreading. Journal of Biological Chemistry (280) 6879-6889.
        • 관련 제품 및 어플리케이션

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          카테고리

          Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Proteases Inhibitors > Calpain Inhibitors