218829 Caspase-3 Substrate IX, Fluorogenic - Calbiochem

218829
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      218829-1MGCN
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          Plastic ampoule 1 mg
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          Description
          OverviewA non-fluorescent peptidyl (DEVD)-Rhodamine 110-bisamide that acts as a highly sensitive, photostable caspase-3 fluorogenic substrate. Reported to detect less than 1 ng/ml of caspase-3. Useful for high throughput screening applications.
          Catalogue Number218829
          Brand Family Calbiochem®
          Synonyms(Z-DEVD)₂-Rh 110
          References
          ReferencesHug, H., et al. 1999. Biochemistry 38, 13906.
          Liu, J., et al. 1999. Bioorg. Med. Chem. Lett. 9, 3231.
          Product Information
          ATP CompetitiveN
          FormYellow lyophilized solid
          FormulationSupplied as a trifluoroacetate salt.
          Hill FormulaC₇₂H₇₈N₁₀O₂₇
          Chemical formulaC₇₂H₇₈N₁₀O₂₇
          ReversibleN
          Quality LevelMQ100
          Applications
          Biological Information
          Primary TargetA highly sensitive, photostable caspase-3 fluorogenic substrate
          Purity≥95% by HPLC
          Physicochemical Information
          Cell permeableN
          Emission max.
          Excitation max.
          Peptide Sequence(Z-Asp-Glu-Val-Asp)₂-Rhodamine 110
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Blue Ice Only
          Toxicity Standard Handling
          Storage -20°C
          Protect from Light Protect from light
          Protect from Moisture Protect from moisture
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Packaged under inert gas Packaged under inert gas
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          Caspase-3 Substrate IX, Fluorogenic - Calbiochem MSDS

          타이틀

          물질안전보건자료(MSDS) 

          Caspase-3 Substrate IX, Fluorogenic - Calbiochem Certificates of Analysis

          TitleLot Number
          218829

          References

          참고문헌 보기
          Hug, H., et al. 1999. Biochemistry 38, 13906.
          Liu, J., et al. 1999. Bioorg. Med. Chem. Lett. 9, 3231.

          Brochure

          Title
          Caspases and other Apoptosis Related Tools Brochure
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision05-June-2008 RFH
          Synonyms(Z-DEVD)₂-Rh 110
          DescriptionA non-fluorescent peptidyl (DEVD)-Rhodamine 110-bisamide that acts as a highly sensitive, photo-stable caspase-3 fluorogenic substrate. Reported to detect less than 1 ng/ml of caspase-3. Also reported to detect capase-3 activity in intact cells by flow cytometry. Useful for high throughput screening applications. Excitation max: ~485 nm; emission max: ~535 nm.
          FormYellow lyophilized solid
          FormulationSupplied as a trifluoroacetate salt.
          Intert gas (Yes/No) Packaged under inert gas
          Chemical formulaC₇₂H₇₈N₁₀O₂₇
          Peptide Sequence(Z-Asp-Glu-Val-Asp)₂-Rhodamine 110
          Purity≥95% by HPLC
          SolubilityDMSO (1 mg/ml)
          Storage -20°C
          Protect from moisture
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Standard Handling
          ReferencesHug, H., et al. 1999. Biochemistry 38, 13906.
          Liu, J., et al. 1999. Bioorg. Med. Chem. Lett. 9, 3231.