219478 Cdk4 Inhibitor III - CAS 265312-55-8 - Calbiochem

219478
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      개요

      Replacement Information

      주요 사양표

      Empirical FormulaCAS #
      C₁₅H₁₂N₂O₂S 265312-55-8

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      카탈로그 번호 재고 정보패킹 포장 단위 가격(VAT 별도) 수량
      219478-5MGCN
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          Plastic ampoule 5 mg
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          Description
          OverviewA cell-permeable dioxobenzothiazole compound that acts a selective Cdk4 inhibitor (IC50 = 6.0 µM for Cdk4/D1 and > 200 µM for Cdk2/A). Exhibit better cytotoxic potential against cancer cells (IC50 = 0.61, 1.08, 0.30, and 1.21 µg/ml against A 549, Col 1, HL-60, and HepG2 tumor cells, respectively) than Cisplatin (Cat. No. 232120).
          Catalogue Number219478
          Brand Family Calbiochem®
          Synonyms5-(N-(4-Methylphenyl)amino)-2-methyl-4,7-dioxobenzothiazole, Ryuvidine
          References
          ReferencesRyu, C.K., et al. 2000. Bioorg. Med. Chem. Lett. 10, 461.
          Product Information
          CAS number265312-55-8
          ATP CompetitiveN
          FormBlack-purple solid
          Hill FormulaC₁₅H₁₂N₂O₂S
          Chemical formulaC₁₅H₁₂N₂O₂S
          ReversibleN
          Structure formula ImageStructure formula Image
          Quality LevelMQ100
          Applications
          Biological Information
          Primary TargetCdk4
          Primary Target IC<sub>50</sub>6.0 µM for Cdk4/D1 and > 200 µM for Cdk2/A
          Purity≥90% by HPLC
          Physicochemical Information
          Cell permeableY
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage +2°C to +8°C
          Protect from Light Protect from light
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Packaged under inert gas Packaged under inert gas
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          Cdk4 Inhibitor III - CAS 265312-55-8 - Calbiochem MSDS

          타이틀

          물질안전보건자료(MSDS) 

          Cdk4 Inhibitor III - CAS 265312-55-8 - Calbiochem Certificates of Analysis

          TitleLot Number
          219478

          References

          참고문헌 보기
          Ryu, C.K., et al. 2000. Bioorg. Med. Chem. Lett. 10, 461.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision11-October-2013 JSW
          Synonyms5-(N-(4-Methylphenyl)amino)-2-methyl-4,7-dioxobenzothiazole, Ryuvidine
          DescriptionA cell-permeable dioxobenzothiazole compound that acts a selective Cdk4 inhibitor (IC50 = 6.0 µM for Cdk4/D1 and >200 µM for Cdk2/A). Exhibit better cytotoxic potential against cancer cells (IC50 = 0.61, 1.08, 0.30, and 1.21 µg/ml against A 549, Col 1, HL-60, and HepG2 tumor cells, respectively) than Cisplatin (Cat. No. 232120).
          FormBlack-purple solid
          Intert gas (Yes/No) Packaged under inert gas
          CAS number265312-55-8
          Chemical formulaC₁₅H₁₂N₂O₂S
          Structure formulaStructure formula
          Purity≥90% by HPLC
          SolubilityDMSO (10 mg/ml)
          Storage +2°C to +8°C
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Standard Handling
          ReferencesRyu, C.K., et al. 2000. Bioorg. Med. Chem. Lett. 10, 461.