230950 Ciglitazone - CAS 74772-77-3 - Calbiochem

230950
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      개요

      Replacement Information

      주요 사양표

      Empirical FormulaCAS #
      C₁₈H₂₃NO₃S 74772-77-3

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      230950-5MGCN
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          Plastic ampoule 5 mg
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          Description
          OverviewA potent thiazolinedione (TDZ) type anti-hyperglycemic agent and a selective PPARγ agonist (EC50 = 3 µM).
          Catalogue Number230950
          Brand Family Calbiochem®
          Synonyms(±)-5-[4-(1-Methylcyclohexylmethoxy)benzyl]thiazolidine-2,4-dione, PPAR Agonist II, PPARγ Agonist I
          References
          ReferencesJha, R.J. 1999. Clin. Exp. Hypertens. 21, 157.
          Xin, X., et al. 1999. J. Biol. Chem. 274, 9116.
          Lohrke, B., et al. 1998. J. Endocrinol. 159, 429.
          Willson, T.M., et al. 1996. J. Med. Chem. 39, 665.
          Cantello, B.C., et al. 1994. J. Med. Chem. 37, 3977.
          Product Information
          CAS number74772-77-3
          ATP CompetitiveN
          FormWhite to tan solid
          Hill FormulaC₁₈H₂₃NO₃S
          Chemical formulaC₁₈H₂₃NO₃S
          ReversibleN
          Structure formula ImageStructure formula Image
          Quality LevelMQ100
          Applications
          Biological Information
          Primary TargetSelective PPARγ agonist
          Primary Target IC<sub>50</sub>EC50 = 3 µM as PPARγ agonist
          Purity≥98% by HPLC
          Physicochemical Information
          Cell permeableN
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          RTECSXJ5813700
          Safety Information
          R PhraseR: 20/21/22

          Harmful by inhalation, in contact with skin and if swallowed.
          S PhraseS: 36

          Wear suitable protective clothing.
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Harmful
          Storage +2°C to +8°C
          Do not freeze Ok to freeze
          Special InstructionsStock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          Ciglitazone - CAS 74772-77-3 - Calbiochem MSDS

          타이틀

          물질안전보건자료(MSDS) 

          Ciglitazone - CAS 74772-77-3 - Calbiochem Certificates of Analysis

          TitleLot Number
          230950

          References

          참고문헌 보기
          Jha, R.J. 1999. Clin. Exp. Hypertens. 21, 157.
          Xin, X., et al. 1999. J. Biol. Chem. 274, 9116.
          Lohrke, B., et al. 1998. J. Endocrinol. 159, 429.
          Willson, T.M., et al. 1996. J. Med. Chem. 39, 665.
          Cantello, B.C., et al. 1994. J. Med. Chem. 37, 3977.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision27-January-2020 JSW
          Synonyms(±)-5-[4-(1-Methylcyclohexylmethoxy)benzyl]thiazolidine-2,4-dione, PPAR Agonist II, PPARγ Agonist I
          DescriptionA potent thiazolinedione (TDZ) type anti-hyperglycemic agent and a selective peroxisome proliferator-activated receptor γ (PPARγ) agonist (EC50 = 3 µM).
          FormWhite to tan solid
          CAS number74772-77-3
          RTECSXJ5813700
          Chemical formulaC₁₈H₂₃NO₃S
          Structure formulaStructure formula
          Purity≥98% by HPLC
          SolubilityDMSO (≥ 25 mg/ml) or Ethanol (≥25 mg/ml)
          Storage +2°C to +8°C
          Do Not Freeze Ok to freeze
          Special InstructionsStock solutions are stable for up to 3 months at -20°C.
          Toxicity Harmful
          ReferencesJha, R.J. 1999. Clin. Exp. Hypertens. 21, 157.
          Xin, X., et al. 1999. J. Biol. Chem. 274, 9116.
          Lohrke, B., et al. 1998. J. Endocrinol. 159, 429.
          Willson, T.M., et al. 1996. J. Med. Chem. 39, 665.
          Cantello, B.C., et al. 1994. J. Med. Chem. 37, 3977.